Pathogenesis of Candida albicans biofilm

C Tsui, EF Kong, MA Jabra-Rizk - FEMS Pathogens and …, 2016 - academic.oup.com
Candida albicans is the most common human fungal pathogen causing diseases ranging
from mucosal to systemic infections. As a commensal, C. albicans asymptomatically …

Candida glabrata, Candida parapsilosis and Candida tropicalis: biology, epidemiology, pathogenicity and antifungal resistance

S Silva, M Negri, M Henriques, R Oliveira… - FEMS microbiology …, 2012 - academic.oup.com
The incidence of infections caused by Candida species (candidosis) has increased
considerably over the past three decades, mainly due to the rise of the AIDS epidemic, an …

ESCMID* guideline for the diagnosis and management of Candida diseases 2012: non‐neutropenic adult patients

OA Cornely, M Bassetti, T Calandra… - Clinical Microbiology …, 2012 - Wiley Online Library
Clin Microbiol Infect 2012; 18 (Suppl. 7): 19–37 Abstract This part of the EFISG guidelines
focuses on non‐neutropenic adult patients. Only a few of the numerous recommendations …

In vitro and in vivo model systems to study microbial biofilm formation

T Coenye, HJ Nelis - Journal of microbiological methods, 2010 - Elsevier
Biofilm formation is often considered the underlying reason why treatment with an
antimicrobial agent fails and as an estimated 65–80% of all human infections is thought to …

Recent insights into Candida albicans biofilm resistance mechanisms

L Mathé, P Van Dijck - Current genetics, 2013 - Springer
Like other microorganisms, free-living Candida albicans is mainly present in a three-
dimensional multicellular structure, which is called a biofilm, rather than in a planktonic form …

Echinocandins in antifungal pharmacotherapy

A Patil, S Majumdar - Journal of Pharmacy and Pharmacology, 2017 - academic.oup.com
Objectives Echinocandins are the newest addition of the last decade to the antifungal
armamentarium, which, owing to their unique mechanism of action, selectively target the …

Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms

N Delattin, BPA Cammue… - Future medicinal …, 2014 - Taylor & Francis
Invasive fungal infections are associated with very high mortality rates ranging from 20–90%
for opportunistic fungal pathogens such as Candida albicans, Cryptococcus neoformans …

Risk factors and outcomes of candidemia caused by biofilm-forming isolates in a tertiary care hospital

M Tumbarello, B Fiori, EM Trecarichi, P Posteraro… - PloS one, 2012 - journals.plos.org
Background Very few data exist on risk factors for developing biofilm-forming Candida
bloodstream infection (CBSI) or on variables associated with the outcome of patients treated …

Antifungal susceptibility of Candida albicans in biofilms

S Tobudic, C Kratzer, A Lassnigg, E Presterl - Mycoses, 2012 - Wiley Online Library
Candida albicans are the most common fungi associated with biofilm‐related infections.
Biofilms are defined as microbial communities encased in a matrix of extracellular polymeric …

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

PV Dijck, J Sjollema, B Cammue, K Lagrou… - Microbial Cell, 2018 - aura.abdn.ac.uk
Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …