The lung microenvironment: an important regulator of tumour growth and metastasis

NK Altorki, GJ Markowitz, D Gao, JL Port… - Nature Reviews …, 2019 - nature.com
Lung cancer is a major global health problem, as it is the leading cause of cancer-related
deaths worldwide. Major advances in the identification of key mutational alterations have led …

The integration of radiotherapy with immunotherapy for the treatment of non–small cell lung cancer

EC Ko, D Raben, SC Formenti - Clinical Cancer Research, 2018 - AACR
Five-year survival rates for non–small cell lung cancer (NSCLC) range from 14% to 49% for
stage I to stage IIIA disease, and are< 5% for stage IIIB/IV disease. Improvements have been …

Insights into lung cancer immune-based biology, prevention, and treatment

S Saab, H Zalzale, Z Rahal, Y Khalifeh… - Frontiers in …, 2020 - frontiersin.org
Lung cancer is the number one cause of cancer-related deaths. The malignancy is
characterized by dismal prognosis and poor clinical outcome mostly due to advanced-stage …

Neoadjuvant immunotherapy for non–small cell lung cancer: State of the art

J Kang, C Zhang, WZ Zhong - Cancer Communications, 2021 - Wiley Online Library
Lung cancer mortality has decreased over the past decade and can be partly attributed to
advances in targeted therapy and immunotherapy. Immune checkpoint inhibitors (ICIs) have …

Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA

JD Finkle, H Boulos, TM Driessen, C Lo… - NPJ Precision …, 2021 - nature.com
Liquid biopsy is a valuable precision oncology tool that is increasingly used as a non-
invasive approach to identify biomarkers, detect resistance mutations, monitor disease …

[HTML][HTML] Lung cancer and oncolytic virotherapy——enemy's enemy

Z Li, Z Feiyue, L Gaofeng, L Haifeng - Translational Oncology, 2023 - Elsevier
Lung cancer is one of the malignant tumors that seriously threaten human health worldwide,
while the covid-19 virus has become people's nightmare after the coronavirus pandemic …

[HTML][HTML] Combining stereotactic body radiation therapy with immunotherapy: current data and future directions

AJ Lin, M Roach, J Bradley… - Translational Lung Cancer …, 2019 - ncbi.nlm.nih.gov
Stereotactic body radiation therapy (SBRT) offers excellent local control of early-stage non-
small cell lung cancer (NSCLC), but there currently is a need for tolerable systemic therapy …

Jinfukang inhibits lung cancer metastasis by upregulating CX3CL1 to recruit NK cells to kill CTCs

ZJ Que, JL Yao, ZY Zhou, P Yu, B Luo, HG Li… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Circulating tumor cells (CTCs) play an important role in
tumor metastasis and may be a target for metastasis prevention. The traditional Chinese …

Exploring the evolving scope of neoadjuvant immunotherapy in NSCLC

JF Roller, NK Veeramachaneni, J Zhang - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapy with immune checkpoint inhibitors has recently brought a
paradigm shift in the treatment of non-small cell lung cancer (NSCLC), but until now, most …

Combination immunotherapy strategies in advanced non-small cell lung cancer (NSCLC): does biological rationale meet clinical needs?

I Attili, A Passaro, A Pavan, PF Conte… - Critical reviews in …, 2017 - Elsevier
Immune checkpoint inhibitors (ICIs) have emerged as one of the main new therapeutic
options for advanced non-small cell lung cancer (NSCLC) patients. Even though they …