Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes

ME Carey, ZA Dyson, DJ Ingle, A Amir, MK Aworh… - Elife, 2023 - elifesciences.org
Background: The Global Typhoid Genomics Consortium was established to bring together
the typhoid research community to aggregate and analyse Salmonella enterica serovar …

Shifting targets: typhoid's transformation from an environmental to a vaccine-preventable disease, 1940–2019

E Webster, PP Lopez, C Kirchhelle - The Lancet Infectious Diseases, 2024 - thelancet.com
Summary 160 years after the discovery of its waterborne transmission and 120 years after
the development of the first-generation of vaccines, typhoid fever remains a major health …

Taking on typhoid: eliminating typhoid fever as a global health problem

J Chen, JE Long, K Vannice… - Open Forum …, 2023 - academic.oup.com
Typhoid fever is a significant global health problem that impacts people living in areas
without access to clean water and sanitation. However, collaborative international …

Detecting Residual Chronic Salmonella Typhi Carriers on the Road to Typhoid Elimination in Santiago, Chile, 2017–2019

RM Lagos, MJ Sikorski, JC Hormazábal… - The Journal of …, 2023 - academic.oup.com
Abstract Background In Santiago, Chile, where typhoid had been hyperendemic (1977–
1991), we investigated whether residual chronic carriers could be detected among …

Early host immune responses in a human organoid-derived gallbladder monolayer to Salmonella Typhi strains from patients with acute and chronic infections: a …

R Salerno-Goncalves, H Chen, AC Bafford… - Frontiers in …, 2024 - frontiersin.org
Salmonella enterica serovar Typhi (S. Typhi), a human-restricted pathogen, invades the host
through the gut to cause typhoid fever. Recent calculations of the typhoid fever burden …

Global diversity and antimicrobial resistance of typhoid fever pathogens: insights from 13,000 Salmonella Typhi genomes

ME Carey, ZA Dyson, DJ Ingle, A Amir, MK Aworh… - medRxiv, 2022 - medrxiv.org
Abstract The Global Typhoid Genomics Consortium was established to bring together the
typhoid research community to aggregate and analyse Salmonella enterica serovar Typhi …

Exploring SNP Filtering Strategies: The Influence of Strict vs Soft Core

ML Taouk, LA Featherstone, G Taiaroa, T Seemann… - bioRxiv, 2024 - biorxiv.org
Phylogenetic analyses are crucial for understanding microbial evolution and infectious
disease transmission. Bacterial phylogenies are often inferred from single nucleotide …

[PDF][PDF] Variant Analysis of XDR Salmonella Typhi Strains Using Global Alignment Tool Kit in South Asian Region

M Niazi, Z Mumtaz, M Ahmed, S Ahmed, A Ali… - Life and …, 2024 - ojs.lifenscience.org
ORIGINAL ARTICLE Variant Analysis of XDR Salmonella Typhi Strains Using Global
Alignment Tool Kit in South Asian Region Page 1 ORIGINAL ARTICLE many countries. The …

Persistence of rare Salmonella Typhi genotypes susceptible to first-line antibiotics in the remote islands of Samoa

MJ Sikorski, TH Hazen, SN Desai, S Nimarota-Brown… - Mbio, 2022 - Am Soc Microbiol
For decades, the remote island nation of Samoa (population~ 200,000) has faced endemic
typhoid fever despite improvements in water quality, sanitation, and economic development …

Genomics and host response of S. Typhi infections

M Maes - 2022 - repository.cam.ac.uk
Genomics and host response to S. Typhi infections Mailis Maes, Department of Medicine, St.
Edmunds College, University of Cambridge Around 20 million people are diagnosed …