A promising candidate: heparin‐binding protein steps onto the stage of sepsis prediction

Y Yang, G Liu, Q He, J Shen, L Xu… - Journal of …, 2019 - Wiley Online Library
Sepsis is a systemic inflammatory response syndrome caused by infection. With high
morbidity and mortality of this disease, there is a need to find early effective diagnosis and …

[HTML][HTML] Harnessing human papillomavirus' natural tropism to target tumors

RC Kines, JT Schiller - Viruses, 2022 - mdpi.com
Human papillomaviruses (HPV) are small non-enveloped DNA tumor viruses established as
the primary etiological agent for the development of cervical cancer. Decades of research …

[HTML][HTML] Leishmaniasis and glycosaminoglycans: a future therapeutic strategy?

DA Merida-de-Barros, SP Chaves, CLR Belmiro… - Parasites & vectors, 2018 - Springer
Leishmania spp. depend on effective macrophage infection to establish and develop in
mammalian hosts. Both metacyclic promastigotes and amastigotes are able to infect host …

[HTML][HTML] Reprogramming of Trypanosoma cruzi metabolism triggered by parasite interaction with the host cell extracellular matrix

EC Mattos, G Canuto, NC Manchola… - PLoS neglected …, 2019 - journals.plos.org
Trypanosoma cruzi, the etiological agent of Chagas' disease, affects 8 million people
predominantly living in socioeconomic underdeveloped areas. T. cruzi trypomastigotes (Ty) …

[HTML][HTML] Immunothrombotic dysregulation in chagas disease and COVID-19: a comparative study of anticoagulation

L Pérez-Campos Mayoral… - Molecular and Cellular …, 2021 - Springer
Chagas and COVID-19 are diseases caused by Trypanosoma cruzi and SARS-CoV-2,
respectively. These diseases present very different etiological agents despite showing …

Extracellular amastigotes of Trypanosoma cruzi are potent inducers of phagocytosis in mammalian cells

MC Fernandes, AR Flannery, N Andrews… - Cellular …, 2013 - Wiley Online Library
The protozoan parasite T rypanosoma cruzi, the aetiological agent of C hagas' disease, has
two infective life cycle stages, trypomastigotes and amastigotes. While trypomastigotes …

Roles of Trypanosoma cruzi calreticulin in parasite–host interactions and in tumor growth

G Ramírez, C Valck, L Aguilar, U Kemmerling… - Molecular …, 2012 - Elsevier
In Latin America, there are about 10–12 million people infected with Trypanosoma cruzi, the
agent of Chagas' disease, one of the most important neglected tropical parasitism …

Requirement of microtubules for secretion of a micronemal protein CpTSP4 in the invasive stage of the apicomplexan Cryptosporidium parvum

D Wang, P Jiang, X Wu, Y Zhang, C Wang, M Li, M Liu… - Mbio, 2024 - Am Soc Microbiol
The zoonotic Cryptosporidium parvum is a global contributor to infantile diarrheal diseases
and opportunistic infections in immunocompromised or weakened individuals. Like other …

[HTML][HTML] Trypanosoma cruzi extracellular amastigotes and host cell signaling: more pieces to the puzzle

ÉR Ferreira, A Bonfim-Melo, RA Mortara… - Frontiers in …, 2012 - frontiersin.org
Among the different infective stages that Trypanosoma cruzi employs to invade cells,
extracellular amastigotes (EAs) have recently gained attention by our group. This is true …

The Gp85 Surface Glycoproteins from Trypanosoma cruzi

EC Mattos, RR Tonelli, W Colli, MJM Alves - Proteins and Proteomics of …, 2014 - Springer
Trypanosoma cruzi strains show distinctive characteristics as genetic polymorphism and
infectivity. Large repertoires of molecules, such as the Gp85 glycoproteins, members of the …