Neuroendocrine tumours.

MT Barakat, K Meeran, SR Bloom - Endocrine-related cancer, 2004 - erc.bioscientifica.com
Neuroendocrine tumours are a heterogeneous group including, for example, carcinoid,
gastroenteropancreatic neuroendocrine tumours, pituitary tumours, medullary carcinoma of …

Multiple endocrine neoplasia type 1: clinical and genetic topics

S Marx, AM Spiegel, MC Skarulis… - Annals of internal …, 1998 - acpjournals.org
Multiple endocrine neoplasia type 1 (MEN1) consists of benign, and sometimes malignant,
tumors (often multiple in a tissue) of the parathyroids, enteropancreatic neuroendocrine …

[图书][B] Pathology and genetics of tumours of endocrine organs

RA DeLellis - 2004 - books.google.com
This volume covers tumors of the pituary, the thyroid and parathyroid, the adrenal gland, the
endocrine pancreas, and inherited tumor syndromes. Each entity is extensively discussed …

Somatic mutation of the MEN1 gene in parathyroid tumours

C Heppner, MB Kester, SK Agarwal, LV Debelenko… - Nature …, 1997 - nature.com
Primary hyperparathyroidism is a common disorder with an annual incidence of
approximately 0.5 in 1,000 (ref. 1). In more than 95% of cases, the disease is caused by …

Somatic Mutations of the MEN1 Tumor Suppressor Gene in Sporadic Gastrinomas and Insulinomas

Z Zhuang, AO Vortmeyer, S Pack, S Huang, TA Pham… - Cancer research, 1997 - AACR
Gastrinomas and insulinomas are frequent in multiple endocrine neoplasia type 1 (MEN1).
The MEN1 tumor suppressor gene was recently identified. To elucidate the etiological role of …

Identification of MEN1 Gene Mutations in Sporadic Carcinoid Tumors of the Lung

LV Debelenko, E Brambilla, SK Agarwal… - Human molecular …, 1997 - academic.oup.com
Lung carcinoids occur sporadically and rarely in association with multiple endocrine
neoplasia type 1 (MEN1). There are no well defined genetic abnormalities known to occur in …

Genetics of neuroendocrine and carcinoid tumours.

PD Leotlela, A Jauch, H Holtgreve-Grez… - Endocrine-related …, 2003 - erc.bioscientifica.com
Neuroendocrine tumours (NETs) originate in tissues that contain cells derived from the
embryonic neural crest, neuroectoderm and endoderm. Thus, NETs occur at many sites in …

Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to …

B Görtz, J Roth, A Krähenmann, RR de Krijger… - The American journal of …, 1999 - Elsevier
Endocrine pancreatic tumors (EPT) and neuroendocrine tumors (NET) occur sporadically
and rarely in association with multiple endocrine neoplasia type 1 (MEN1). We analyzed the …

Genetic changes in the spectrum of neuroendocrine lung tumors

N Onuki, II Wistuba, WD Travis… - … Journal of the …, 1999 - Wiley Online Library
BACKGROUND Recent classifications identify four categories of neuroendocrine (NE)
tumors of the lung: low grade typical carcinoid (TC), intermediate grade atypical carcinoid …

[HTML][HTML] The future: genetics advances in MEN1 therapeutic approaches and management strategies

SK Agarwal - Endocrine-related cancer, 2017 - ncbi.nlm.nih.gov
The identification of the multiple endocrine neoplasia type 1 (MEN1) gene in 1997 has
shown that germline heterozygous mutations in the MEN1 gene located on chromosome …