Exosome processing and characterization approaches for research and technology development

JJ Lai, ZL Chau, SY Chen, JJ Hill… - Advanced …, 2022 - Wiley Online Library
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …

Nanostructured particles assembled from natural building blocks for advanced therapies

Y Ju, H Liao, JJ Richardson, J Guo… - Chemical Society …, 2022 - pubs.rsc.org
Advanced treatments based on immune system manipulation, gene transcription and
regulation, specific organ and cell targeting, and/or photon energy conversion have …

Electrical stimulation as a novel tool for regulating cell behavior in tissue engineering

C Chen, X Bai, Y Ding, IS Lee - Biomaterials research, 2019 - spj.science.org
Recently, electrical stimulation as a physical stimulus draws lots of attention. It shows great
potential in disease treatment, wound healing, and mechanism study because of significant …

Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles

A Sahu, ZJ Clemens, SN Shinde, S Sivakumar, A Pius… - Nature aging, 2021 - nature.com
Heterochronic blood exchange (HBE) has demonstrated that circulating factors restore
youthful features to aged tissues. However, the systemic mediators of those rejuvenating …

Extracellular vesicles as personalized medicine

DJ Beetler, DN Di Florio, KA Bruno, T Ikezu… - Molecular aspects of …, 2023 - Elsevier
Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …

Extracellular vesicles and exosomes: insights from exercise science

JP Nederveen, G Warnier, A Di Carlo… - Frontiers in …, 2021 - frontiersin.org
The benefits of exercise on health and longevity are well-established, and evidence
suggests that these effects are partially driven by a spectrum of bioactive molecules …

[HTML][HTML] Exosomal DMBT1 from human urine-derived stem cells facilitates diabetic wound repair by promoting angiogenesis

CY Chen, SS Rao, L Ren, XK Hu, YJ Tan, Y Hu… - Theranostics, 2018 - ncbi.nlm.nih.gov
Chronic non-healing wounds represent one of the most common complications of diabetes
and need advanced treatment strategies. Exosomes are key mediators of cell paracrine …

Exosome biogenesis, secretion and function of exosomal miRNAs in skeletal muscle myogenesis

B Yue, H Yang, J Wang, W Ru, J Wu, Y Huang… - Cell …, 2020 - Wiley Online Library
Exosomes are membrane‐bound extracellular vesicles that are produced in the endosomal
compartment of most mammalian cell types and then released. Exosomes are effective …

Engineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells

G Liang, S Kan, Y Zhu, S Feng, W Feng… - International journal of …, 2018 - Taylor & Francis
Introduction Exosomes are closed-membrane nanovesicles that are secreted by a variety of
cells and exist in most body fluids. Recent studies have demonstrated the potential of …

In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo: Part I: Health and Normal Physiology

AG Yates, RC Pink, U Erdbrügger… - Journal of …, 2022 - Wiley Online Library
Previously thought to be nothing more than cellular debris, extracellular vesicles (EVs) are
now known to mediate physiological and pathological functions throughout the body. We …