[HTML][HTML] Intravenous parecoxib for pain relief after orthopedic surgery: a systematic review and meta-analysis

X Li, P Zhou, Z Li, H Tang, S Zhai - Pain and therapy, 2022 - Springer
Introduction Orthopedic procedures have been associated with increased pain, making
perioperative analgesia a major clinical concern. We assessed the efficacy and safety of …

普通外科围手术期疼痛处理专家共识

冷希圣, 韦军民, 刘连新, 江志伟, 吴育连, 何裕隆… - 中华普通外科 …, 2015 - cqvip.com
普通外科围手术期疼痛处理专家共识-[维普官方网站]-www.cqvip.com-维普网  我的维普 购物车
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[HTML][HTML] COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice

D Vardeh, D Wang, M Costigan… - The Journal of …, 2009 - Am Soc Clin Investig
A cardinal feature of peripheral inflammation is pain. The most common way of managing
inflammatory pain is to use nonsteroidal antiinflammatory agents (NSAIDs) that reduce …

Efficacy and Safety of Postoperative Pain Relief by Parecoxib Injection after Laparoscopic Surgeries: A Systematic Review and Meta‐analysis of Randomized …

J Huang, Z Lv, Y Zhang, W Jiang, H Li, M Nie - Pain Practice, 2018 - Wiley Online Library
Objective This study aims to evaluate the efficacy and safety of parecoxib injection in pain
relief after laparoscopic surgeries. Methods A comprehensive literature search based on 4 …

The cyclooxygenase-2 inhibitor parecoxib inhibits surgery-induced proinflammatory cytokine expression in the hippocampus in aged rats

M Peng, YL Wang, FF Wang, C Chen… - Journal of Surgical …, 2012 - Elsevier
BACKGROUND: Neuroinflammatory response triggered by surgery has been increasingly
reported to be associated with postoperative cognitive dysfunction. Proinflammatory …

Preincisional versus postincisional administration of parecoxib in colorectal surgery: effect on postoperative pain control and cytokine response. A randomized clinical …

A Pandazi, E Kapota, P Matsota… - World journal of …, 2010 - Springer
Background Preincisional pain management aims at reducing pain and inflammatory
response. We investigated whether preincisional parecoxib administration reduces pain …

帕瑞昔布钠在腹腔镜结肠癌根治术中的超前镇痛作用

王庆, 李真, 王志鹏, 崔灿 - 南方医科大学学报, 2010 - cqvip.com
目的观察帕瑞昔布钠对腹腔镜结肠癌根治术的超前镇痛作用. 方法40 例30~ 64 岁, ASAI~ II
级择期行腹腔镜结肠癌根治术病人, 随机分为两组, 在麻醉诱导时(A 组) 或手术结束前30min (B …

Intratumoral COX‐2 inhibition enhances GM‐CSF immunotherapy against established mouse GL261 brain tumors

S Eberstål, E Sandén, S Fritzell… - … journal of cancer, 2014 - Wiley Online Library
Immunotherapy has shown effectiveness against experimental malignant brain tumors, but
the clinical results have been less convincing most likely due to immunosuppression …

[HTML][HTML] Multi-dose parecoxib provides an immunoprotective effect by balancing T helper 1 (Th1), Th2, Th17 and regulatory T cytokines following laparoscopy in …

W Ma, K Wang, J Du, J Luan… - Molecular Medicine …, 2015 - spandidos-publications.com
Analgesic treatment with anti‑inflammatory drugs may aid the prevention of postoperative
pain and the attenuation of the postoperative immune inflammatory response. The current …

帕瑞昔布临床应用进展

郑月钗, 陈萍 - 西部医学, 2011 - cqvip.com
非甾体抗炎药(non—steroid anti—inflammatory drugs, NSAIDs) 在术后镇痛中的应用日益广泛.
由于传统NSAIDs 的胃肠道毒性和血小板抑制作用, 临床应用受到限制. 帕瑞昔布钠是唯一可 …