Advances in atherosclerosis imaging technology and research have provided a range of
diagnostic tools to characterize high-risk plaque in vivo; however, these important vascular …

The cardiovascular science community has pursued the quest to identify vulnerable
atherosclerotic plaque in patients for decades, hoping to prevent acute coronary events …

Importance Coronary plaques that are prone to rupture and cause adverse cardiac events
are characterized by large plaque burden, large lipid content, and thin fibrous caps. Statins …

Background Current guidelines recommend dual antiplatelet therapy (DAPT) of aspirin plus
a P2Y12 inhibitor for at least 12 months after implantation of drug-eluting stents (DES) in …

Objectives: The aim of the present study was to evaluate the ability of optical coherence
tomography (OCT) for assessment of the culprit lesion morphology in acute myocardial …

Background—The current understanding of the pathophysiology of coronary artery disease
is based largely on postmortem studies. Optical coherence tomography (OCT) is a high …

Background: A lack of clarity exists about the role of complete coronary revascularization in
patients presenting with non–ST-segment elevation myocardial infarction. Objectives: The …

Aim The effect of long-term high-intensity statin therapy on coronary atherosclerosis among
patients with acute ST-segment elevation myocardial infarction (STEMI) is unknown. The …

Background—In the absence of previous international comparisons, we sought to
systematically evaluate, across time and participant age, the sex ratio in angina prevalence …

Atherosclerosis is the main cause of coronary heart disease, which is today the leading
cause of death worldwide and will continue to be the first in the world in 2030. In the …