Zebrafish: A complete animal model to enumerate the nanoparticle toxicity
C Chakraborty, AR Sharma, G Sharma… - Journal of …, 2016 - Springer
Presently, nanotechnology is a multi-trillion dollar business sector that covers a wide range
of industries, such as medicine, electronics and chemistry. In the current era, the commercial …
of industries, such as medicine, electronics and chemistry. In the current era, the commercial …
Zebrafish models of neurodevelopmental disorders: past, present, and future
C Sakai, S Ijaz, EJ Hoffman - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Zebrafish are increasingly being utilized as a model system to investigate the function of the
growing list of risk genes associated with neurodevelopmental disorders. This is due in large …
growing list of risk genes associated with neurodevelopmental disorders. This is due in large …
The zebrafish reference genome sequence and its relationship to the human genome
Zebrafish have become a popular organism for the study of vertebrate gene function,. The
virtually transparent embryos of this species, and the ability to accelerate genetic studies by …
virtually transparent embryos of this species, and the ability to accelerate genetic studies by …
High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9
GK Varshney, W Pei, MC LaFave, J Idol, L Xu… - Genome …, 2015 - genome.cshlp.org
The use of CRISPR/Cas9 as a genome-editing tool in various model organisms has
radically changed targeted mutagenesis. Here, we present a high-throughput targeted …
radically changed targeted mutagenesis. Here, we present a high-throughput targeted …
An Indexed, Mapped Mutant Library Enables Reverse Genetics Studies of Biological Processes in Chlamydomonas reinhardtii
The green alga Chlamydomonas reinhardtii is a leading unicellular model for dissecting
biological processes in photosynthetic eukaryotes. However, its usefulness has been limited …
biological processes in photosynthetic eukaryotes. However, its usefulness has been limited …
[HTML][HTML] Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy
The use of adeno-associated virus (AAV) as a gene therapy vector has been approved
recently for clinical use and has demonstrated efficacy in a growing number of clinical trials …
recently for clinical use and has demonstrated efficacy in a growing number of clinical trials …
The Zebrafish Information Network: new support for non-coding genes, richer Gene Ontology annotations and the Alliance of Genome Resources
L Ruzicka, DG Howe, S Ramachandran… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Zebrafish Information Network (ZFIN)(https://zfin. org/) is the database for the
model organism, zebrafish (Danio rerio). ZFIN expertly curates, organizes and provides a …
model organism, zebrafish (Danio rerio). ZFIN expertly curates, organizes and provides a …
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
BE Housden, M Muhar, M Gemberling… - Nature Reviews …, 2017 - nature.com
Our understanding of the genetic mechanisms that underlie biological processes has relied
extensively on loss-of-function (LOF) analyses. LOF methods target DNA, RNA or protein to …
extensively on loss-of-function (LOF) analyses. LOF methods target DNA, RNA or protein to …
A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish
GK Varshney, B Carrington, W Pei, K Bishop, Z Chen… - Nature protocols, 2016 - nature.com
The zebrafish is a popular model organism for studying development and disease, and
genetically modified zebrafish provide an essential tool for functional genomic studies …
genetically modified zebrafish provide an essential tool for functional genomic studies …
Expanding the CRISPR toolbox in zebrafish for studying development and disease
The study of model organisms has revolutionized our understanding of the mechanisms
underlying normal development, adult homeostasis, and human disease. Much of what we …
underlying normal development, adult homeostasis, and human disease. Much of what we …