[HTML][HTML] DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer
DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
Novel diagnostic biomarkers in colorectal cancer
AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …
Epigenetic alterations in colorectal cancer: emerging biomarkers
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …
fundamental processes driving the initiation and progression of CRC is the accumulation of …
[HTML][HTML] Colorectal cancer: from prevention to personalized medicine
G Binefa, F Rodríguez-Moranta, À Teule… - World journal of …, 2014 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a very heterogeneous disease that is caused by the interaction
of genetic and environmental factors. CRC develops through a gradual accumulation of …
of genetic and environmental factors. CRC develops through a gradual accumulation of …
Next-generation stool DNA test accurately detects colorectal cancer and large adenomas
DA Ahlquist, H Zou, M Domanico, DW Mahoney… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Technical advances have led to stool DNA (sDNA) tests that might
accurately detect neoplasms on both sides of the colorectum. We assessed colorectal …
accurately detect neoplasms on both sides of the colorectum. We assessed colorectal …
Methylation of TFPI2 in Stool DNA: A Potential Novel Biomarker for the Detection of Colorectal Cancer
SC Glöckner, M Dhir, JM Yi, KE McGarvey… - Cancer research, 2009 - AACR
We have used a gene expression array–based strategy to identify the methylation of tissue
factor pathway inhibitor 2 (TFPI2), a potential tumor suppressor gene, as a frequent event in …
factor pathway inhibitor 2 (TFPI2), a potential tumor suppressor gene, as a frequent event in …
[HTML][HTML] Colon cancer screening methods: 2023 update
M Jayasinghe, O Prathiraja, D Caldera, R Jena… - Cureus, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a significant cause of morbidity and mortality worldwide. National
screening guidelines have been implemented to identify and remove precancerous polyps …
screening guidelines have been implemented to identify and remove precancerous polyps …
Molecular detection of colorectal neoplasia
DA Ahlquist - Gastroenterology, 2010 - Elsevier
A variety of noninvasive molecular approaches to colorectal cancer screening are emerging
with potential to improve screening effectiveness and user-friendliness. These approaches …
with potential to improve screening effectiveness and user-friendliness. These approaches …
Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression
AEK Ibrahim, MJ Arends, AL Silva, AH Wyllie, L Greger… - Gut, 2011 - gut.bmj.com
Background and aims Although aberrant methylation of key genes in the progression of
colorectal neoplasia has been reported, no model-based analysis of the incremental …
colorectal neoplasia has been reported, no model-based analysis of the incremental …
Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
GE Lind, SA Danielsen, T Ahlquist, MA Merok… - Molecular cancer, 2011 - Springer
Background The presence of cancer-specific DNA methylation patterns in epithelial
colorectal cells in human feces provides the prospect of a simple, non-invasive screening …
colorectal cells in human feces provides the prospect of a simple, non-invasive screening …