The role of miRNAs in dexmedetomidine's neuroprotective effects against brain disorders

CC Burlacu, MA Neag, AO Mitre, AC Sirbu… - International Journal of …, 2022 - mdpi.com
There are limited neuroprotective strategies for various central nervous system conditions in
which fast and sustained management is essential. Neuroprotection-based therapeutics …

Toxicology of Specific Substances

AW Jones, F Musshoff, T Krämer… - … of Forensic Medicine, 2022 - Wiley Online Library
Ethanol intoxication and drunkenness are underlying factors in many fatal poisonings, either
alone or combined with other psychoactive substances ingested together with ethanol. The …

The MAP2K4/JNK/c-jun signaling pathway plays a key role in dexmedetomidine protection against acetaminophen-induced liver toxicity

AH Chou, CC Liao, HC Lee, JT Liou… - Drug Design …, 2019 - Taylor & Francis
Purpose Dexmedetomidine [DEX;(S)-4-[1-(2, 3-dimethylphenyl) ethyl]-3H-imidazole] is a
selective α2-adrenergic receptor (α2-AR) agonist that attenuates the liver damage …

[PDF][PDF] Glutathione S-Transferase (A1) as a marker of Acute Acetaminophen Induced Hepatotoxicity and Nephrotoxicity, and the Protective Role of Dexmedetomidine

AM Abdel-Moez - Minia Journal of Medical Research, 2020 - mjmr.journals.ekb.eg
Background: acetaminophen (APAP) is an important drug that cause nephrotoxicity and
hepatictoxicity in high dose. Glutathione S-transferase A1 (GSTA1) is a marker that used to …