Current perspectives on recurrent HPV-mediated oropharyngeal cancer

T Guo, SY Kang, EEW Cohen - Frontiers in Oncology, 2022 - frontiersin.org
In the recent years, the prevalence of HPV-positive oropharyngeal squamous cell carcinoma
(OPSCC) has increased significantly. Currently, nearly 80-90% of all oropharynx tumors are …

Circulating human papillomavirus DNA in head and neck squamous cell carcinoma: possible applications and future directions

D Adilbay, S Lele, J Pang, A Asarkar, J Calligas… - Cancers, 2022 - mdpi.com
Simple Summary Circulating human papillomavirus DNA is a promising tool in the
management of HPV-positive oropharyngeal cancer. The potential use of this tool will …

Performance of liquid biopsy for diagnosis and surveillance of human papillomavirus–associated oropharyngeal cancer

RM Ferrandino, S Chen, C Kappauf… - … –Head & Neck …, 2023 - jamanetwork.com
Importance There is growing interest in the use of circulating plasma tumor human
papillomavirus (HPV) DNA for diagnosis and surveillance of patients with HPV-associated …

Circulating tumor-tissue modified HPV DNA testing in the clinical evaluation of patients at risk for HPV-positive oropharynx cancer: The IDEA-HPV study

S Batool, RKV Sethi, A Wang, K Dabekaussen… - Oral Oncology, 2023 - Elsevier
Objectives While survival outcomes are favorable for Human Papillomavirus (HPV)-positive
oropharyngeal squamous cell carcinomas (OPSCCs), early diagnosis may minimize …

Tumor-derived exosomes and the role of liquid biopsy in human papillomavirus oropharyngeal squamous cell carcinoma

MM Allevato, JD Smith, MJ Brenner… - The Cancer …, 2023 - journals.lww.com
The global incidence of human papillomavirus–positive (HPV+) head and neck squamous
cell carcinoma (HNSCC) has surged in recent decades, with HPV+ HNSCC accounting for> …

Emerging roles of circulating tumor DNA for increased precision and personalization in radiation oncology

N Earland, K Chen, NP Semenkovich… - Seminars in Radiation …, 2023 - Elsevier
Recent breakthroughs in circulating tumor DNA (ctDNA) technologies present a compelling
opportunity to combine this emerging liquid biopsy approach with the field of radiogenomics …

It is time to improve the diagnostic workup of oropharyngeal cancer with circulating tumor HPV DNA: Systematic review and meta‐analysis

F Paolini, F Campo, O Iocca, V Manciocco… - Head & …, 2023 - Wiley Online Library
The possibility of detecting circulating tumor HPV DNA (ctHPVDNA) in plasma in patients
with oropharyngeal cancer has been demonstrated in several reports. However, these data …

Contemporary Imaging and Reporting Strategies for Head and Neck Cancer: MRI, FDG PET/MRI, NI-RADS, and Carcinoma of Unknown Primary—AJR Expert Panel …

S Mukherjee, NJ Fischbein… - American Journal of …, 2023 - Am Roentgen Ray Soc
CT, MRI, and FDG PET/CT play major roles in the diagnosis, staging, treatment planning,
and surveillance of head and neck cancers. Nonetheless, an evolving understanding of …

Mitochondrial DNA in circulating exosomes: A novel biomarker and potential therapeutic target for oral cancer

K Balachander, A Roy, JV Priyadharsini… - Oral …, 2022 - pubmed.ncbi.nlm.nih.gov
Mitochondrial DNA in circulating exosomes: A novel biomarker and potential therapeutic target
for oral cancer Mitochondrial DNA in circulating exosomes: A novel biomarker and potential …

Sensitive MRD detection from lymphatic fluid after surgery in HPV-associated oropharyngeal cancer

N Earland, NP Semenkovich, RJ Ramirez… - Clinical Cancer …, 2024 - AACR
Purpose: Our goal was to demonstrate that lymphatic drainage fluid (lymph) has improved
sensitivity in quantifying postoperative minimal residual disease (MRD) in locally advanced …