Smac mimetics can provoke lytic cell death that is neither apoptotic nor necroptotic
Smac mimetics, or IAP antagonists, are a class of drugs currently being evaluated as anti-
cancer therapeutics. These agents antagonize IAP proteins, including cIAP1/2 and XIAP, to …
cancer therapeutics. These agents antagonize IAP proteins, including cIAP1/2 and XIAP, to …
Tetrazolium reduction assays under-report cell death provoked by clinically relevant concentrations of proteasome inhibitors
High throughput cell viability screening assays often capitalize on the ability of active
enzymes or molecules within viable cells to catalyze a quantifiable chemical reaction. The …
enzymes or molecules within viable cells to catalyze a quantifiable chemical reaction. The …
[HTML][HTML] Sodium Channel Signal
Smac mimetics, or IAP antagonists, are a class of drugs currently being evaluated as anti-
cancer therapeutics. These agents antagonize IAP proteins, including cIAP1/2 and XIAP, to …
cancer therapeutics. These agents antagonize IAP proteins, including cIAP1/2 and XIAP, to …