BackgroundIt is well established that people with irritable bowel syndrome (IBS) have higher
levels of anxiety and depression compared with controls. However, the role of these as risk …

There is increasing evidence that the composition of the resident bacteria within the
gastrointestinal tract can influence the brain and behavior, particularly with respect to …

Psychological interventions have been designed and implemented effectively in a wide
range of medical conditions, including Irritable Bowel Syndrome (IBS) and Inflammatory …

Abstract Serotonin (5‐hydroxytryptophan [5‐HT]) is a biologically active amine expressed in
platelets, in gastrointestinal (GI) cells and, to a lesser extent, in the central nervous system …

Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder of unknown
etiology. Although relatively common in children, how this condition affects brain structure …

Background Stress is an exacerbator of irritable bowel syndrome (IBS) symptoms, and
anxiety and depression are co‐morbidities. Bifidobacterium longum strains 1714® and …

Introduction Individuals with IBS report higher levels of psychological distress compared to
healthy controls. Distress has been associated with emotional processing difficulties but …

Irritable bowel syndrome (IBS), a gastrointestinal disease, is a global phenomenon
correlated with industrialization. We propose that an evolutionary medicine approach is …

Abstract Evidence-Based Medicine has little consideration for mechanisms and
philosophers of science and medicine have recently made pleas to increase the place of …

Background Globus is a persistent or intermittent nonpainful sensation of a lump or foreign
body, which markedly affect patient's quality of life. Treatment options for globus are limited …