The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …

The field of non-coding RNA (ncRNA) has made significant progress in understanding the
pathogenesis of diseases and has broadened our knowledge towards their targeting …

Simple Summary Cytokines are important molecular players in cancer development,
progression, and potential targets for treatment. Despite being small and overlooked …

Matrix metalloproteinases (MMPs) are identifiable members of proteolytic enzymes that can
degrade a wide range of proteins in the extracellular matrix (ECM). MMPs can be …

Heart failure (HF) is an acute or chronic clinical syndrome that results in a decrease in
cardiac output and an increase in intracardiac pressure at rest or upon exertion. The …

Keratoconus (KC) is a serious disease that can affect people of any race or nationality,
although the exact etiology and pathogenic mechanism are still unknown. In this study, thirty …

Abstract Histone deacetylase 8 (HDAC8) aberrantly deacetylates histone and non-histone
proteins. These include structural maintenance of chromosome 3 (SMC3) cohesin protein …

Among various matrix metalloproteinases (MMPs), MMPs having medium-size S1′ pockets
are established as promising biomolecular targets for executing crucial roles in cancer …

Tumour metastasis is one of the major factors leading to poor prognosis as well as lower
survival among cancer patients. A number of studies investigating the inhibition of tumour …

The breast cancer tumor microenvironment (TME) is dynamic, with various immune and non-
immune cells interacting to regulate tumor progression and anti-tumor immunity. It is now …