[HTML][HTML] Revisiting metallodrugs for the treatment of skin cancers

CM Manzano, DH Nakahata, REF de Paiva - Coordination Chemistry …, 2022 - Elsevier
Metallodrugs were classically screened against skin cancer (either in vitro or in vivo) at the
peak of the development of platinum anticancer agents. New systematic studies appeared in …

Synthesis, structure and characterization of new dithiocarbazate-based mixed ligand oxidovanadium (IV) complexes: DNA/HSA interaction, cytotoxic activity and DFT …

A Banerjee, M Mohanty, S Lima, R Samanta… - New Journal of …, 2020 - pubs.rsc.org
Three new mixed-ligand oxidovanadium (IV) complexes [VIVOL1–2 (LN–N)](1–3) have
been synthesized using two tridentate bi-negative–ONS chelating dithiocarbazate ligands …

Transport of the Ruthenium Complex [Ru(GA)(dppe)2]PF6 into Triple-Negative Breast Cancer Cells Is Facilitated by Transferrin Receptors

MA Naves, AE Graminha, LC Vegas… - Molecular …, 2019 - ACS Publications
The triple-negative breast cancer subtype (TNBC) is highly aggressive and metastatic and
corresponds to 15–20% of diagnosed cases. TNBC treatment is hampered, because these …

Ruthenium complexes with mono- or bis-heterocyclic chelates: DNA/BSA binding, antioxidant and anticancer studies

S Maikoo, A Chakraborty, N Vukea… - Journal of …, 2021 - Taylor & Francis
Deoxyribonucleic acid (DNA) and bovine serum albumin (BSA) binding interactions for a
series of ruthenium heterocyclic complexes were monitored using ultraviolet-visible (UV-Vis) …

Photochemistry of ruthenium nitrosyl complexes in solids and solutions and its potential applications

AA Mikhailov, ED Stolyarova, GA Kostin - Journal of Structural Chemistry, 2021 - Springer
The review is devoted to photochemical transformations of ruthenium nitrosyl complexes in
various media and their potential applications in the context of these transformations …

Ruthenium (II) diphosphine complexes with mercapto ligands that inhibit topoisomerase IB and suppress tumor growth in vivo

MM da Silva, GH Ribeiro, MS de Camargo… - Inorganic …, 2021 - ACS Publications
Ruthenium (II) complexes (Ru1–Ru5), with the general formula [Ru (NS)(dppe) 2] PF6,
bearing two 1, 2-bis (diphenylphosphino) ethane (dppe) ligands and a series of mercapto …

Beyond metal-arenes: Monocarbonyl ruthenium (II) catalysts for transfer hydrogenation reactions in water and in cells

D Lovison, T Berghausen, SR Thomas, J Robson… - ACS …, 2023 - ACS Publications
With the aim to design water-soluble organometallic Ru (II) complexes acting as anticancer
agents catalyzing transfer hydrogenation (TH) reactions with biomolecules, we have …

Ruthenium (II) complex cis-[RuII2-O2CC7H7O2)(dppm)2]PF6-hmxbato induces ROS-mediated apoptosis in lung tumor cells producing selective …

MS Costa, YG Gonçalves, BC Borges, MJB Silva… - Scientific Reports, 2020 - nature.com
Ruthenium complexes have been extensively explored as potential molecules for cancer
treatment. Considering our previous findings on the remarkable cytotoxic activity exhibited …

Enantioselective Cytotoxicity of Chiral Diphosphine Ruthenium (II) Complexes Against Cancer Cells

D Lovison, D Alessi, L Allegri, F Baldan… - … A European Journal, 2022 - Wiley Online Library
The chiral cationic complex [Ru (η1‐OAc)(CO)((R, R)‐Skewphos)(phen)] OAc (2R), isolated
from reaction of [Ru (η1‐OAc)(η2‐OAc)(R, R)‐Skewphos)(CO)](1R) with phen, reacts with …

Phosphine/diimine ruthenium complexes with Cl−, CO, NO+, NO2−, NO3− and pyridine ligands: Pro-apoptotic activity on triple-negative breast cancer cells and DNA …

HVR Silva, JSM Dias, GA Ferreira-Silva, LC Vegas… - Polyhedron, 2018 - Elsevier
A series of five new ruthenium phosphine/diimine complexes were prepared and
characterized by IR, UV–Vis, 1 H, 31 P {1 H} and 13 C {1 H} NMR spectroscopies, elemental …