Mouse embryo phenotyping with optical coherence tomography

DM Scully, IV Larina - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
With the explosion of gene editing tools in recent years, there has been a much greater
demand for mouse embryo phenotyping, and traditional methods such as histology and …

Teratogenic effects of maternal drug abuse on developing brain and underlying neurotransmitter mechanisms

B Little, N Sud, Z Nobile, D Bhattacharya - Neurotoxicology, 2021 - Elsevier
The aim of this review is to highlight our knowledge of the various drugs of abuse that can
prove potential teratogens affecting the brain and cognitive development in an individual …

Embryonic mouse cardiodynamic OCT imaging

AL Lopez III, S Wang, IV Larina - Journal of Cardiovascular Development …, 2020 - mdpi.com
The embryonic heart is an active and developing organ. Genetic studies in mouse models
have generated great insight into normal heart development and congenital heart defects …

Dose-response analysis of microvasculature changes in the murine fetal brain and the maternal extremities due to prenatal ethanol exposure

R Raghunathan, CH Liu, A Kouka… - Journal of …, 2020 - spiedigitallibrary.org
Significance: Prenatal exposure to ethanol causes several morphological and
neurobehavioral deficits. While there are some studies on the effects of ethanol exposure on …

Assessing the effects of prenatal poly-drug exposure on fetal brain vasculature using optical coherence angiography

R Raghunathan, J Gutierrez, CH Liu… - Journal of …, 2023 - spiedigitallibrary.org
Significance Maternal exposure to drugs during pregnancy is known to have detrimental
effects on the fetus. Alcohol (ethanol) and nicotine are two of the most commonly co-abused …

Motion Artifact Correction for OCT Microvascular Images Based on Image Feature Matching

X Chen, Z Ma, C Wang, J Cui, F Fan… - Journal of …, 2024 - Wiley Online Library
Optical coherence tomography angiography (OCTA), a functional extension of optical
coherence tomography (OCT), is widely employed for high‐resolution imaging of …

Quantitative OCT angiography toward 4D blood flow analysis in embryonic cardiovascular system

MA McCown, IV Larina - Dynamics and Fluctuations in …, 2023 - spiedigitallibrary.org
Alterations in cardiac development lead to embryonic lethality or congenital heart defects,
which affect about 1% of all newborns worldwide. The heart is critical for blood circulation to …

A comparison of microvasculature changes in the fetal brain and maternal extremities due to prenatal alcohol exposure using optical coherence angiography

R Raghunathan, CH Liu, M Singh… - … and Fluctuations in …, 2021 - spiedigitallibrary.org
Prenatal alcohol exposure (PAE) causes a spectrum of abnormalities, collectively termed as
fetal alcohol spectrum disorders (FASD). The severity of the defect depends on the amount …

Dose-response analysis of microvasculature changes in the murine fetal brain and the maternal extremities due to prenatal ethanol exposure

M Singh, RC Miranda, KV Larin - Journal of Biomedical Optics, 2020 - spiedigitallibrary.org
Significance: Prenatal exposure to ethanol causes several morphological and
neurobehavioral deficits. While there are some studies on the effects of ethanol exposure on …

Impatto della Tossicodipendenza Genitoriale sullo Sviluppo Cerebrale e Sociale nei Bambini

G BONDURI - thesis.unipd.it
La ricerca si concentra su come l'esposizione alle sostanze stupefacenti durante la
gravidanza e l'infanzia influenzi la neuroplasticità, lo sviluppo emotivo e lo sviluppo sociale …