The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …

[HTML][HTML] COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection

S Beyerstedt, EB Casaro, ÉB Rangel - European journal of clinical …, 2021 - Springer
COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Angiotensin-
converting enzyme 2 (ACE2) is not only an enzyme but also a functional receptor on cell …

Risk factors for severe and critically ill COVID‐19 patients: a review

Y Gao, M Ding, X Dong, J Zhang, A Kursat Azkur… - Allergy, 2021 - Wiley Online Library
The pandemic of coronavirus disease 2019 (COVID‐19), caused by the severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused an unprecedented global …

[HTML][HTML] COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup

MK Nadim, LG Forni, RL Mehta, MJ Connor Jr… - Nature reviews …, 2020 - nature.com
Kidney involvement in patients with coronavirus disease 2019 (COVID-19) is common, and
can range from the presence of proteinuria and haematuria to acute kidney injury (AKI) …

Infectious Diseases Society of America Guidelines on the treatment and management of patients with coronavirus disease 2019 (COVID-19)

A Bhimraj, RL Morgan, AH Shumaker… - Clinical Infectious …, 2020 - academic.oup.com
Background There are many pharmacologic therapies that are being used or considered for
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …

[HTML][HTML] COVID-19 and diabetes: understanding the interrelationship and risks for a severe course

CP Landstra, EJP de Koning - Frontiers in endocrinology, 2021 - frontiersin.org
The relationship between COVID-19 and diabetes mellitus is complicated and bidirectional.
On the one hand, diabetes mellitus is considered one of the most important risk factors for a …

Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): a review

WJ Wiersinga, A Rhodes, AC Cheng, SJ Peacock… - Jama, 2020 - jamanetwork.com
Importance The coronavirus disease 2019 (COVID-19) pandemic, due to the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a worldwide sudden …

Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people

J Hippisley-Cox, D Young, C Coupland, KM Channon… - Heart, 2020 - heart.bmj.com
Background There is uncertainty about the associations of angiotensive enzyme (ACE)
inhibitor and angiotensin receptor blocker (ARB) drugs with COVID-19 disease. We studied …

Factors leading to high morbidity and mortality of COVID‐19 in patients with type 2 diabetes

A Rajpal, L Rahimi, F Ismail‐Beigi - Journal of diabetes, 2020 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is a recent pandemic caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a novel coronavirus. Diabetes …

[HTML][HTML] Cuadro clínico del COVID-19

R Gil, P Bitar, C Deza, J Dreyse, M Florenzano… - Revista Médica Clínica …, 2021 - Elsevier
Resumen El Coronavirus SARS-CoV-2 produce la enfermedad COVID-19, cuya
manifestación más grave y potencialmente letal es la neumonía. En este artículo …