Paracetamol: new vistas of an old drug

A Bertolini, A Ferrari, A Ottani, S Guerzoni… - CNS drug …, 2006 - Wiley Online Library
Paracetamol (acetaminophen) is one of the most popular and widely used drugs for the
treatment of pain and fever. It occupies a unique position among analgesic drugs. Unlike …

Pathogenesis of human immunodeficiency virus infection

JA Levy - Microbiological reviews, 1993 - Am Soc Microbiol
The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

Antiviral polymers: past approaches and future possibilities

RH Bianculli, JD Mase, MD Schulz - Macromolecules, 2020 - ACS Publications
Treating a viral disease is no simple feat. Drug resistance, latent reservoirs in the body,
emerging novel viruses, and a frequent lack of specific treatments all complicate antiviral …

[图书][B] Fields' virology

BN Fields - 2007 - books.google.com
Established for 20 years as the definitive virology reference, the two-volume classic Fields
Virology is in its thoroughly revised, updated Fifth Edition. More than 100 world-renowned …

Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity

B Fromenty, D Pessayre - Pharmacology & therapeutics, 1995 - Elsevier
Severe and prolonged impairment of mitochondrial β-oxidation leads to microvesicular
steatosis, and, in severe forms, to liver failure, coma and death. Impairment of mitochondrial …

HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

BA Larder, G Darby, DD Richman - Science, 1989 - science.org
The drug sensitivities of human immunodeficiency virus (HIV) isolates from a group of
patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) …

Estimating the lost benefits of antiretroviral drug use in South Africa

P Chigwedere, GR Seage III, S Gruskin… - JAIDS Journal of …, 2008 - journals.lww.com
South Africa is one of the countries most severely affected by HIV/AIDS. At the peak of the
epidemic, the government, going against consensus scientific opinion, argued that HIV was …

Mitochondrial toxicity of antiviral drugs

W Lewis, MC Dalakas - Nature medicine, 1995 - nature.com
Long-term treatment with antiviral nucleoside analogue drugs, such as AZT, can give rise to
delayed and at times severe mitochondrial toxicity. Although these toxic effects are manifest …

Epidemiology of anemia in human immunodeficiency virus (HIV)-infected persons: results from the multistate adult and adolescent spectrum of HIV disease …

PS Sullivan, DL Hanson, SY Chu… - Blood, The Journal …, 1998 - ashpublications.org
To study the incidence of, the factors associated with, and the effect on survival of anemia in
human immunodeficiency virus (HIV)-infected persons, we analyzed data from the …

Treatment of human immunodeficiency virus infection with saquinavir, zidovudine, and zalcitabine

AC Collier, RW Coombs, DA Schoenfeld… - … England Journal of …, 1996 - Mass Medical Soc
Background In patients with human immunodeficiency virus (HIV) infection, combined
treatment with several agents may increase the effectiveness of antiviral therapy. We studied …