The basis and advances in clinical application of cytomegalovirus-specific cytotoxic T cell immunotherapy for glioblastoma multiforme

A Daei Sorkhabi, A Sarkesh, H Saeedi, F Marofi… - Frontiers in …, 2022 - frontiersin.org
A high percentage of malignant gliomas are infected by human cytomegalovirus (HCMV),
and the endogenous expression of HCMV genes and their products are found in these …

[HTML][HTML] Integrated clustering signature of genomic heterogeneity, stemness and tumor microenvironment predicts glioma prognosis and immunotherapy response

Y Wu, M Mao, LJ Wang - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Background: Glioma is the most frequent primary tumor of the central nervous system. The
high heterogeneity of glioma tumors enables them to adapt to challenging environments …

Role and Mechanism of Growth Differentiation Factor 15 in Chronic Kidney Disease

Y Tang, T Liu, S Sun, Y Peng, X Huang… - Journal of …, 2024 - Taylor & Francis
GDF-15 is an essential member of the transforming growth factor-beta superfamily. Its
functions mainly involve in tissue injury, inflammation, fibrosis, regulation of appetite and …

Gas plasma exposure of glioblastoma is cytotoxic and immunomodulatory in patient-derived GBM tissue

S Bekeschus, M Ispirjan, E Freund, F Kinnen, J Moritz… - Cancers, 2022 - mdpi.com
Simple Summary Despite treatment advances, glioblastoma multiforme (GBM) remains an
often-fatal disease, motivating novel therapeutic avenues. Gas plasma is a technology that …

GDF-15 Predicts Epithelioid Hemangioendothelioma Aggressiveness and Is Downregulated by Sirolimus through ATF4/ATF5 Suppression

S Stacchiotti, S Martini, S Pasquali… - Clinical Cancer …, 2024 - aacrjournals.org
Abstract Purpose: Epithelioid hemangioendothelioma (EHE), an ultra-rare sarcoma, poses
therapeutic challenges because of limited efficacy of conventional chemotherapy in …

Bulk and single-cell transcriptome revealed the metabolic heterogeneity in human glioma

Y Xiao, M Zhao, R Wang, L Liu, C Xiang, T Li, C Qian… - Heliyon, 2024 - cell.com
Background Emerging perspectives on tumor metabolism reveal its heterogeneity, a
characteristic yet to be fully explored in gliomas. To advance therapies targeting metabolic …

Influence of S1PR1/S1PR2 blocking on growth behavior of glioblastoma cells using the model substances ACT-209905 and Compound 16

F Chen - 2021 - epub.ub.uni-greifswald.de
Glioblastoma multiforme (GBM) is the most common and most aggressive malignant tumor
of the central nervous system in adults. The median survival time of patients suffering from …