This review focuses on the role of prenatal hypoxia in the development of brain functions in
the postnatal period and subsequent increased risk of neurodegenerative disorders in later …

The total number of neurons within six subdivisions of the rat basal ganglia was estimated
using unbiased stereological counting methods and systematic random sampling …

Animal models with partial lesions of the dopaminergic nigrostrital pathway may be useful
for developing neuroprotective and neurotrophic therapies for Parkinson's disease. To …

Mechanisms responsible for 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced
dopamine (DA) neuronal death remain unknown and in mice it is even unclear whether …

Hypoxia threatens brain function during the entire life-span starting from early fetal age up to
senescence. This review compares the short-term, long-term and life-spanning effects of …

There are three main mechanisms of neuronal cell death which may act separately or
cooperatively to cause neurodegeneration. This lethal triplet of metabolic compromise …

Focal brain lesions can lead to metabolic and structural changes in areas distant from but
connected to the lesion site. After focal ischemic or excitotoxic lesions of the cortex and/or …

Brain development is influenced by various prenatal, intrapartum, and postnatal events
which may interact with genotype to affect the neural and psychophysiological systems …

Simple Summary Parkinson's disease is a neurodegenerative disorder characterized by the
death of a specific subset of dopamine-producing neurons. This triggers problems with …

We have previously shown that apoptotic natural cell death occurs within the substantia
nigra (SN) pars compacta of the rat postnatally. However, the occurrence of natural cell …