A review exploring biological activities of hydrazones

G Verma, A Marella, M Shaquiquzzaman… - Journal of Pharmacy …, 2014 - journals.lww.com
The development of novel compounds, hydrazones has shown that they possess a wide
variety of biological activities viz. antimicrobial, anticonvulsant, antidepressant, anti …

N,N-Dialkylhydrazones in Organic Synthesis. From Simple N,N-Dimethylhydrazones to Supported Chiral Auxiliaries

R Lazny, A Nodzewska - Chemical reviews, 2010 - ACS Publications
The well-known properties of the carbonyl group render aldehydes and ketones prominent
substrates in both CC and C-heteroatom bond forming methodologies of organic synthesis …

Participation of Oxidative Stress in the Activity of Compounds Isolated from Eleutherine plicata Herb

ARQ Gomes, JN Cruz, ALG Castro… - Molecules, 2023 - mdpi.com
From Eleutherine plicata, naphthoquinones, isoeleutherine, and eleutherol were isolated,
and previous studies have reported the antioxidant activity of these metabolites. The present …

Meroterpenes from marine invertebrates: Structures, occurrence, and ecological implications

M Menna, C Imperatore, F D'Aniello, A Aiello - Marine Drugs, 2013 - mdpi.com
Meroterpenes are widely distributed among marine organisms; they are particularly
abundant within brown algae, but other important sources include microorganisms and …

Studies on quinones. Part 44: Novel angucyclinone N-heterocyclic analogues endowed with antitumoral activity

JA Valderrama, P Colonelli, D Vásquez… - Bioorganic & medicinal …, 2008 - Elsevier
In the search for new potentially anticancer drugs, series of angucyclinone aza-analogues
containing pyridine and pyridopyridazine rings have been designed and synthesized by a …

Acid‐Catalyzed Activation and Condensation of the =C5H Bond of Furfural on Aldehydes, an Entry Point to Biobased Monomers

S Behloul, O Gayraud, G Frapper, F Guégan… - …, 2024 - Wiley Online Library
Furfural is an industrially relevant biobased chemical platform. Unlike classical furan, or C‐
alkylated furans, which have been previously described in the current literature, the= C5H …

Synthesis, leishmanicidal activity and theoretical evaluations of a series of substituted bis-2-hydroxy-1, 4-naphthoquinones

MV De Araújo, PSO De Souza, AC De Queiroz… - Molecules, 2014 - mdpi.com
A series of eight substituted bis-2-hydroxy-1, 4-naphthoquinone derivatives was synthesized
through lawsone condensation with various aromatic and aliphatic aldehydes under mild …

Molecules of natural origin, semi-synthesis and synthesis with anti-inflammatory and anticancer utilities

A M. Lourenco, L M. Ferreira… - Current pharmaceutical …, 2012 - benthamdirect.com
The development of new drugs that can be valuable for the evolution of diseases' treatment
is a goal for different areas of research, namely natural products chemistry, molecular …

Cytotoxicity and In Vitro Antileishmanial Activity of Antimony (V), Bismuth (V), and Tin (IV) Complexes of Lapachol

MN Rocha, PM Nogueira, C Demicheli… - Bioinorganic …, 2013 - Wiley Online Library
Leishmania amazonensis is the etiologic agent of the cutaneous and diffuse leishmaniasis
often associated with drug resistance. Lapachol [2‐hydroxy‐3‐(3′‐methyl‐2‐butenyl)‐1, 4 …

Hydrazone Activation in the Aminocatalytic Cascade Reaction for the Synthesis of Tetrahydroindolizines

J Kowalska, B Łukasik, S Frankowski, Ł Albrecht - Organic Letters, 2024 - ACS Publications
In this Letter, we demonstrate the usefulness of hydrazone activation for the synthesis of
biologically relevant tetrahydroindolizines. A pyrrol-derived hydrazone bearing a Michael …