The gut microbiota is a rich and dynamic ecosystem that actively interacts with the human
body, playing a significant role in the state of health and disease of the host. Diet, exercise …

Rationale Although precision medicine is seen by many as one of the most promising
advances in the field of medicine, it has also raised critical questions at various levels. Many …

Background Paediatric precision oncology aims to match therapeutic agents to driver gene
targets. We investigated whether parents and patients regret participation in precision …

Fused deposition modelling (FDM) 3D printing provides the ability to address individual
patients' therapeutic needs without having to change the formulation every time. This is …

The use of genome-wide sequencing (GWS) in paediatrics has added complexity to
informed consent (IC) and pretest counselling because of the vast number and interpretation …

Navigating the intricate landscape of the tumor microenvironment (TME) unveils a pivotal
arena for cancer therapeutics, where cytokines and soluble mediators emerge as double …

Background Genetic/genomic testing (GGT) are useful tools for improving health and
preventing diseases. Still, since GGT deals with sensitive personal information that could …

In mammalian cells, signalling pathways orchestrate cellular growth, differentiation and
survival, as well as many other processes that are essential for the proper functioning of …

Clinical applications of artificial intelligence (AI) in healthcare, including in the field of
oncology, have the potential to advance diagnosis and treatment. The literature suggests …

Polygenic risk scores (PRS) may improve risk-stratification in preventive care. Their clinical
implementation will depend on primary care physicians'(PCPs) uptake. We surveyed PCPs …