BACKGROUND: Currently there is no reliable test to predict pathological complete response
following neoadjuvant chemoradiotherapy for rectal cancer. However, there is increasing …

As we mark 150 years since the birth of Marie Curie, we reflect on the global advances
made in radiation oncology and the current status of radiation therapy (RT) research. Large …

The American Society of Colon and Rectal Surgeons (ASCRS) is dedicated to ensuring high-
quality patient care by advancing the science, prevention, and management of disorders …

2.1 Geltungsbereich und Zweck 2.1. 1. Zielsetzung und Fragestellung Das Kolorektale
Karzinom (KRK) ist mit etwa 64 000 Neuerkrankungen und ca. 26 000 Todesfällen pro Jahr …

Background and purpose The RAPIDO trial demonstrated a decrease in disease-related
treatment failure (DrTF) and an increase in pathological complete responses (pCR) in locally …

Background During the past decade there has been considerable progress in developing
new radiation methods for cancer treatment. Pelvic radiotherapy constitutes the primary or …

Colorectal carcinoma is the second leading cause of cancer-related deaths in the United
States, with rectal cancer accounting for approximately one-third of newly diagnosed cases …

Importance A watch-and-wait approach for patients with rectal cancer and a clinical
complete response after neoadjuvant chemoradiotherapy or radiotherapy is associated with …

Simple Summary This prospective phase II–III randomized trial explores the value of modern
technology for prudent radiation dose escalation in the curative management of patients with …

Rectal cancer treatment has witnessed several changes in the past decades resulting into
improved outcomes. 1 Preoperative radiotherapy is much better tolerated than postoperative …