Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

A systematic review of published toxicology and human intervention studies was performed
to characterize potential hazards associated with consumption of green tea and its …

Down syndrome (also known as trisomy 21) is the model human phenotype for all genomic
gain dosage imbalances, including microduplications. The functional genomic exploration of …

Abstract Background Green tea (Camellia sinensis) is a beverage consumed for thousands
of years. Numerous claims about the benefits of its consumption were stated and …

Abstract The EFSA ANS Panel was asked to provide a scientific opinion on the safety of
green tea catechins from dietary sources including preparations such as food supplements …

Dual-specificity tyrosine phosphorylation-regulated kinase 1 A (DYRK1A) is a conserved
protein kinase that plays essential roles in various biological processes. It is located in the …

Background Early cognitive intervention is the only routine therapeutic approach used for
amelioration of intellectual deficits in individuals with Down's syndrome, but its effects are …

Polyphenols are an important class of phytochemicals, and several lines of evidence have
demonstrated their beneficial effects in the context of a number of pathologies including …

Down's syndrome is the most common genetic cause of learning difficulties, and individuals
with this condition represent the largest group of people with dementia under the age of 50 …

Schizophrenia is a complex, chronic mental health disorder whose heterogeneous genetic
and neurobiological background influences early brain development, and whose precise …