Role of sulphur-heterocycles in medicinal chemistry: An update

S Pathania, RK Narang, RK Rawal - European journal of medicinal …, 2019 - Elsevier
From many decades, S-heterocycles have maintained their status as an important part and
core of FDA approved drugs and medicinally active compounds. With exhaustive exploration …

Synthetic and medicinal perspective of quinolines as antiviral agents

R Kaur, K Kumar - European Journal of Medicinal Chemistry, 2021 - Elsevier
In current scenario, various heterocycles have come up exhibiting crucial role in various
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …

A conceptual review of rhodanine: current applications of antiviral drugs, anticancer and antimicrobial activities

SM Mousavi, M Zarei, SA Hashemi… - Artificial cells …, 2019 - Taylor & Francis
Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the
4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and …

A systematic review of synthetic tyrosinase inhibitors and their structure-activity relationship

Z Peng, G Wang, QH Zeng, Y Li, H Liu… - Critical Reviews in …, 2022 - Taylor & Francis
Tyrosinase is a copper-containing oxidation enzyme, which is responsible for the production
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …

In vitro and in silico studies of fluorinated 2, 3‐disubstituted thiazolidinone‐pyrazoles as potential α‐amylase inhibitors and antioxidant agents

D Ganavi, R Ramu, V Kumar, SM Patil… - Archiv der …, 2022 - Wiley Online Library
As part of our effort to identify potent α‐amylase inhibitors, in the present study, a novel
series of fluorinated thiazolidinone‐pyrazole hybrid molecules were prepared by the …

In vitro and in vivo evaluation of the antimicrobial, antioxidant, cytotoxic, hemolytic activities and in silico POM/DFT/DNA-binding and pharmacokinetic analyses of …

SA Hassan, DM Aziz, MN Abdullah… - Journal of …, 2024 - Taylor & Francis
In this work, Schiff bases and Thiazolidin-4-ones, were synthesized using Sonication and
Microwave techniques, respectively. The Schiff base derivatives (3a–b) were synthesized …

A new series of 2, 4-thiazolidinediones endowed with potent aldose reductase inhibitory activity

B Sever, MD Altıntop, Y Demir, C Türkeş, K Özbaş… - Open …, 2021 - degruyter.com
In an effort to identify potent aldose reductase (AR) inhibitors, 5-(arylidene) thiazolidine-2, 4-
diones (1–8), which were prepared by the solvent-free reaction of 2, 4-thiazolidinedione with …

Antitubercular properties of thiazolidin-4-ones–A review

N Trotsko - European Journal of Medicinal Chemistry, 2021 - Elsevier
Thiazolidin-4-one scaffold has great potential for medicinal chemistry and is of interest to
scientists in view of wide spectrum of biological activity. This scaffold is often used for …

Role and treatment of insulin resistance in patients with chronic kidney disease: a review

A Nakashima, K Kato, I Ohkido, T Yokoo - Nutrients, 2021 - mdpi.com
Patients with chronic kidney disease (CKD) and dialysis have higher mortality than those
without, and cardiovascular disease (CVD) is the main cause of death. As CVD is caused by …

Identification of 1, 3, 4-Thiadiazolyl-Containing Thiazolidine-2, 4-dione Derivatives as Novel PTP1B Inhibitors with Antidiabetic Activity

M Li, H Li, X Min, J Sun, B Liang, L Xu, J Li… - Journal of Medicinal …, 2024 - ACS Publications
Forty-one 1, 3, 4-thiadiazolyl-containing thiazolidine-2, 4-dione derivatives (MY1–41) were
designed and synthesized as protein tyrosine phosphatase 1B (PTP1B) inhibitors with …