Role of sulphur-heterocycles in medicinal chemistry: An update
From many decades, S-heterocycles have maintained their status as an important part and
core of FDA approved drugs and medicinally active compounds. With exhaustive exploration …
core of FDA approved drugs and medicinally active compounds. With exhaustive exploration …
Synthetic and medicinal perspective of quinolines as antiviral agents
In current scenario, various heterocycles have come up exhibiting crucial role in various
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …
A conceptual review of rhodanine: current applications of antiviral drugs, anticancer and antimicrobial activities
Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the
4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and …
4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and …
A systematic review of synthetic tyrosinase inhibitors and their structure-activity relationship
Z Peng, G Wang, QH Zeng, Y Li, H Liu… - Critical Reviews in …, 2022 - Taylor & Francis
Tyrosinase is a copper-containing oxidation enzyme, which is responsible for the production
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …
In vitro and in silico studies of fluorinated 2, 3‐disubstituted thiazolidinone‐pyrazoles as potential α‐amylase inhibitors and antioxidant agents
As part of our effort to identify potent α‐amylase inhibitors, in the present study, a novel
series of fluorinated thiazolidinone‐pyrazole hybrid molecules were prepared by the …
series of fluorinated thiazolidinone‐pyrazole hybrid molecules were prepared by the …
In vitro and in vivo evaluation of the antimicrobial, antioxidant, cytotoxic, hemolytic activities and in silico POM/DFT/DNA-binding and pharmacokinetic analyses of …
SA Hassan, DM Aziz, MN Abdullah… - Journal of …, 2024 - Taylor & Francis
In this work, Schiff bases and Thiazolidin-4-ones, were synthesized using Sonication and
Microwave techniques, respectively. The Schiff base derivatives (3a–b) were synthesized …
Microwave techniques, respectively. The Schiff base derivatives (3a–b) were synthesized …
A new series of 2, 4-thiazolidinediones endowed with potent aldose reductase inhibitory activity
In an effort to identify potent aldose reductase (AR) inhibitors, 5-(arylidene) thiazolidine-2, 4-
diones (1–8), which were prepared by the solvent-free reaction of 2, 4-thiazolidinedione with …
diones (1–8), which were prepared by the solvent-free reaction of 2, 4-thiazolidinedione with …
Antitubercular properties of thiazolidin-4-ones–A review
N Trotsko - European Journal of Medicinal Chemistry, 2021 - Elsevier
Thiazolidin-4-one scaffold has great potential for medicinal chemistry and is of interest to
scientists in view of wide spectrum of biological activity. This scaffold is often used for …
scientists in view of wide spectrum of biological activity. This scaffold is often used for …
Role and treatment of insulin resistance in patients with chronic kidney disease: a review
A Nakashima, K Kato, I Ohkido, T Yokoo - Nutrients, 2021 - mdpi.com
Patients with chronic kidney disease (CKD) and dialysis have higher mortality than those
without, and cardiovascular disease (CVD) is the main cause of death. As CVD is caused by …
without, and cardiovascular disease (CVD) is the main cause of death. As CVD is caused by …
Identification of 1, 3, 4-Thiadiazolyl-Containing Thiazolidine-2, 4-dione Derivatives as Novel PTP1B Inhibitors with Antidiabetic Activity
M Li, H Li, X Min, J Sun, B Liang, L Xu, J Li… - Journal of Medicinal …, 2024 - ACS Publications
Forty-one 1, 3, 4-thiadiazolyl-containing thiazolidine-2, 4-dione derivatives (MY1–41) were
designed and synthesized as protein tyrosine phosphatase 1B (PTP1B) inhibitors with …
designed and synthesized as protein tyrosine phosphatase 1B (PTP1B) inhibitors with …