IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Maternal serum cytokine concentrations in healthy pregnancy and preeclampsia

T Spence, PJ Allsopp, AJ Yeates… - Journal of …, 2021 - Wiley Online Library
The maternal immune response is essential for successful pregnancy, promoting immune
tolerance to the fetus while maintaining innate and adaptive immunity. Uncontrolled …

Cytokine patterns in maternal serum from first trimester to term and beyond

AH Jarmund, GF Giskeødegård, M Ryssdal… - Frontiers in …, 2021 - frontiersin.org
Pregnancy implies delicate immunological balance between two individuals, with constant
changes and adaptions in response to maternal capacity and fetal demands. We performed …

Chemokine profile in women with moderate to severe anxiety and depression during pregnancy

I Camacho-Arroyo, M Flores-Ramos… - BMC Pregnancy and …, 2021 - Springer
Background Cytokine levels have been extensively described in pregnant subjects under
normal and pathological conditions, including mood-related disorders. Concerning …

Cytokine see‐saw across pregnancy, its related complexities and consequences

A Meyyazhagan, H Kuchi Bhotla… - … of Gynecology & …, 2023 - Wiley Online Library
During pregnancy, a woman's immune system adapts to the changing hormonal
concentrations, causing immunologic transition. These immunologic changes are required …

Physiological and metabolic adaptations in pregnancy: importance of trimester-specific reference intervals to investigate maternal health and complications

MK Bohn, K Adeli - Critical Reviews in Clinical Laboratory Sciences, 2022 - Taylor & Francis
Diagnosis, prognostication, and monitoring of maternal health throughout pregnancy relies
on laboratory testing, including but not limited to key markers of thyroid, hepatic, cardiac …

[HTML][HTML] Stress and depression-associated shifts in gut microbiota: A pilot study of human pregnancy

TA Rajasekera, JD Galley, AR Mackos, HJ Chen… - Brain, Behavior, & …, 2024 - Elsevier
Background Psychosocial stress and mood-related disorders, such as depression, are
prevalent and vulnerability to these conditions is heightened during pregnancy …

Immunomodulatory effects of metformin treatment in pregnant women with PCOS

M Ryssdal, E Vanky, LMT Stokkeland… - The Journal of …, 2023 - academic.oup.com
Context Polycystic ovary syndrome (PCOS) is a common endocrine disorder associated with
low-grade systemic inflammation and increased risk of pregnancy complications. Metformin …

Disgust sensitivity is negatively associated with immune system activity in early pregnancy: Direct support for the Compensatory Prophylaxis Hypothesis

Š Kaňková, L Takács, M Krulová, J Hlaváčová… - Evolution and Human …, 2022 - Elsevier
Abstract According to the Compensatory Prophylaxis Hypothesis (CPH), disgust may be
considered a part of the behavioral immune system, adjusting as a function of …

Inflammatory markers are elevated in early pregnancy, but not late pregnancy, in women with overweight and obesity that later develop preeclampsia

MKK Jancsura, MJ Schmella… - American Journal of …, 2023 - Wiley Online Library
Problem Obesity and preeclampsia both involve a pathological inflammatory response,
which may be how obesity increases preeclampsia risk. Previous studies have failed to …