Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine that acts on multiple cell
lineages, including dendritic cells, T cells, B cells, neutrophils, mast cells, eosinophils and …

Regulatory T cells (Treg cells) are key players in ensuring a peaceful coexistence with
microorganisms and food antigens at intestinal borders. Startling new information has …

Emerging studies indicate that cooperation between neurons and immune cells regulates
antimicrobial immunity, inflammation and tissue homeostasis. For example, a neuronal …

Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …

The interests in intestinal epithelial tuft cells, their basic physiology, involvement in immune
responses and relevance for gut diseases, have increased dramatically over the last fifteen …

Aeroallergen sensing by airway epithelial cells triggers pathogenic immune responses
leading to type 2 inflammation, the hallmark of chronic airway diseases such as asthma. Tuft …

The enteric nervous system (ENS) of the gastrointestinal (GI) tract interacts with the local
immune system bidirectionally. Recent publications have demonstrated that such …

A characteristic feature of host responses to helminth infections is the development of
profound systemic and tissue-localised Type 2 immune responses that play critical roles in …

Type 2 immune responses form a critical defence against enteric worm infections. In recent
years, mouse models have revealed shared and unique functions for group 2 innate …

Innate lymphoid cells (ILCs) are critical mediators of immunological and physiological
responses at mucosal barrier sites. Whereas neurotransmitters can stimulate ILCs, the …