Capsaicin is the active ingredient of chili peppers and gives them the characteristic pungent
flavor. Understanding the actions of capsaicin led to the discovery of its receptor, transient …

The transient receptor potential (TRP) superfamily consists of a large number of cation
channels that are mostly permeable to both monovalent and divalent cations. The 28 …

The clinical use of TRPV1 (transient receptor potential vanilloid subfamily, member 1; also
known as VR1) antagonists is based on the concept that endogenous agonists acting on …

Peripheral mediators can contribute to the development and maintenance of inflammatory
and neuropathic pain and its concomitants (hyperalgesia and allodynia) via two …

The transient receptor potential (TRP) superfamily consists of a large number of
nonselective cation channels with variable degree of Ca2+-permeability. The 28 mammalian …

Caffeine is the most consumed pychostimulant in the world, and it is known to affect basic
and fundamental human processes such as sleep, arousal, cognition and learning and …

Despite optimal combination of guideline-directed anti-ischemic therapies and myocardial
revascularization, a substantial proportion of patients with stable coronary artery disease …

▪ Abstract Angina pectoris often results from ischemic episodes that excite chemosensitive
and mechanoreceptive receptors in the heart. Ischemic episodes release a collage of …

The transient receptor potential (TRP) channel superfamily consists of 28 mammalian cation
channels and is expressed in almost every tissue, including the heart and vasculature; most …

purpose. Elevated hydrostatic pressure induces retinal ganglion cell (RGC) apoptosis in
culture. The authors investigated whether the transient receptor potential vanilloid 1 …