Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …

Parasites of the genus Plasmodium have a complex life cycle. They alternate between their
final mosquito host and their intermediate hosts. The parasite can be either extra-or …

Plasmodium falciparum VAR2CSA binds to chondroitin sulfate A (CSA) on the surface of the
syncytiotrophoblast during placental malaria. This interaction facilitates placental …

The quest for a licensed effective vaccine against malaria remains a global priority. Even
though classical vaccine design strategies have been successful for some viral and bacterial …

In areas where Plasmodium falciparum transmission is endemic, clinical immunity against
malaria is progressively acquired during childhood and adults are usually protected against …

Placental malaria can have severe consequences for both mother and child and effective
vaccines are lacking. Parasite-infected red blood cells sequester in the placenta through …

Two vaccines based on Plasmodium falciparum protein VAR2CSA are currently in clinical
evaluation to prevent placental malaria (PM), but a deeper understanding of var2csa …

Vaccines against infectious diseases have had great successes in the history of public
health. Major breakthroughs have occurred in the development of vaccine-based …

Plasmodium parasites are the causative agent of malaria, a disease that kills approximately
450,000 individuals annually, with the majority of deaths occurring in children under the age …

In this study, we investigated how different categories of prenatal malaria exposure (PME)
influence levels of maternal antibodies in cord blood samples and the subsequent risk of …