Stochastic developmental variation, an epigenetic source of phenotypic diversity with far-reaching biological consequences

G Vogt - Journal of Biosciences, 2015 - Springer
This article reviews the production of different phenotypes from the same genotype in the
same environment by stochastic cellular events, nonlinear mechanisms during patterning …

Unifying individual differences in personality, predictability and plasticity: a practical guide

RE O'Dea, DWA Noble… - Methods in Ecology and …, 2022 - Wiley Online Library
Organisms use labile traits to respond to different conditions over short time‐scales. When a
population experiences the same conditions, we might expect all individuals to adjust their …

Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies

S Patalano, A Vlasova, C Wyatt… - Proceedings of the …, 2015 - National Acad Sciences
Phenotypic plasticity is important in adaptation and shapes the evolution of organisms.
However, we understand little about what aspects of the genome are important in facilitating …

[HTML][HTML] Stochastic simulation in systems biology

T Székely Jr, K Burrage - Computational and structural biotechnology …, 2014 - Elsevier
Natural systems are, almost by definition, heterogeneous: this can be either a boon or an
obstacle to be overcome, depending on the situation. Traditionally, when constructing …

The evolution of variance control

M Bruijning, CJE Metcalf, E Jongejans… - Trends in ecology & …, 2020 - cell.com
Genetically identical individuals can be phenotypically variable, even in constant
environmental conditions. The ubiquity of this phenomenon, known as 'intra-genotypic …

Fitness effects of altering gene expression noise in Saccharomyces cerevisiae

F Duveau, A Hodgins-Davis, BPH Metzger, B Yang… - Elife, 2018 - elifesciences.org
Gene expression noise is an evolvable property of biological systems that describes
differences in expression among genetically identical cells in the same environment. Prior …

Developmental mechanisms underlying variable, invariant and plastic phenotypes

K Abley, JCW Locke, HMO Leyser - Annals of botany, 2016 - academic.oup.com
Background Discussions of phenotypic robustness often consider scenarios where invariant
phenotypes are optimal and assume that developmental mechanisms have evolved to buffer …

The evolutionary ecology of dormancy in nature and in cancer

AK Miller, JS Brown, H Enderling, D Basanta… - Frontiers in Ecology …, 2021 - frontiersin.org
Dormancy is an inactive period of an organism's life cycle that permits it to survive through
phases of unfavorable conditions in highly variable environments. Dormancy is not binary …

An ABA-GA bistable switch can account for natural variation in the variability of Arabidopsis seed germination time

K Abley, P Formosa-Jordan, H Tavares, EYT Chan… - Elife, 2021 - elifesciences.org
Genetically identical plants growing in the same conditions can display heterogeneous
phenotypes. Here we use Arabidopsis seed germination time as a model system to examine …

The evolution of gene-specific transcriptional noise is driven by selection at the pathway level

GV Barroso, N Puzovic, JY Dutheil - Genetics, 2018 - academic.oup.com
Gene expression is a noisy process: in constant environment and genotype, cell to cell
variability occurs because of randomness of biochemical reactions... Biochemical reactions …