66 DWEK ET AL structural diversity of glycans attached to proteins (1), the fact that each
glycosylated polypeptide is generally associated with a population of different glycan …

Contribution of mass spectrometry (MS) in the diagnosis and characterization of congenital
disorders of glycosylation (CDG) has long been known. CDG type I diseases are …

Underivatized neutral oligosaccharides from human milk were analyzed by nano-
electrospray ionization (ESI) using a quadrupole ion trap mass spectrometer (QIT-MS) in the …

A challenging aspect of structural elucidation of carbohydrates is gaining unambiguous
information for anomers, linkage, and position isomers. Such isomers with identical mass …

Side chains of sugar beet (Beta vulgaris) pectins, which are mainly composed of arabinose
(Ara) and galactose (Gal) residues, are esterified by ferulic acid units. Enzymatic hydrolysis …

Newcomers to the field of biopharmaceuticals require an understanding of the basic
principles and underlying methodology involved in developing protein-and nucleic acid …

The sequential tandem mass spectrometry (MS n) capabilities offered by quadrupole ion
trap instruments have been explored in a systematic study of permethylated …

Negative ion electrospray-tandem mass spectrometry has been employed to study chloride
adducts of saccharide molecules. Decompositions of [M+ Cl]− obtained under identical low …

Electrospray tandem mass spectrometry used in conjunction with reversed-phase liquid
chromatography was applied to characterize permethylated oligosaccharides. N …

The spectra recorded by matrix‐assisted laser desorption/ionization time‐of‐flight/time‐of‐
flight tandem mass spectrometry (MALDI‐TOF/TOF‐MS/MS) of complex carbohydrates from …