Osteomyelitis is a major complication of orthopedic diseases with high recurrence and
morbidity, along with long hospital stays and high medical costs. The conventional treatment …

Pseudomonas aeruginosa is a pathogen often encountered in a healthcare setting. It has
consistently ranked among the most frequent pathogens seen in nosocomial infections …

Background Antimicrobial resistance (AMR) is undermining modern medicine, a problem
compounded by bacterial adaptation to antibiotic pressures. Phages are viruses that infect …

Bacteriophages, viruses that infect and replicate within bacteria, impact bacterial responses
to antibiotics in complex ways. Recent studies using lytic bacteriophages to treat bacterial …

Introduction Novel last resort beta-lactam antibiotics are now available for management of
infections due to New-Delhi Metallo-Beta-Lactamase (NDM) producing Enterobacterales …

Solutions for bone and joint infection (BJI) are needed where conventional treatments are
inadequate. Bacteriophages (phages) are naturally occurring viruses that infect bacteria and …

Bacteriophage therapy is one potential strategy to treat antimicrobial resistant or persistent
bacterial infections, and the year 2021 marked the centennial of Felix d'Hérelle's first …

Facing the global “superbug” crisis due to the emergence and selection for antibiotic
resistance, phages are among the most promising solutions. Fighting multidrug-resistant …

Background A growing number of compassionate phage therapy cases were reported in the
last decade, with a limited number of clinical trials conducted and few unsuccessful clinical …

Therapeutic bacteriophages (phages) are primarily chosen based on their in vitro
bacteriolytic activity. Although anti-phage antibodies are known to inhibit phage infection …