[HTML][HTML] Proteome and phospholipidome interrelationship of synovial fluid-derived extracellular vesicles in equine osteoarthritis: An exploratory 'multi-omics' study to …
E Clarke, L Varela, RE Jenkins… - … and Biophysics Reports, 2024 - Elsevier
Osteoarthritis causes progressive joint deterioration, severe morbidity, and reduced mobility
in both humans and horses. Currently, osteoarthritis is diagnosed at late stages through …
in both humans and horses. Currently, osteoarthritis is diagnosed at late stages through …
[HTML][HTML] Therapeutic Application of Extracellular Vesicles Derived from Mesenchymal Stem Cells in Domestic Animals
A Lanci, E Iacono, B Merlo - Animals, 2024 - mdpi.com
Simple Summary Extracellular vesicles (EVs) secreted by mesenchymal stem cells (MSCs)
have recently been described in human and veterinary medicine and great interest is …
have recently been described in human and veterinary medicine and great interest is …
Multi-omic temporal landscape of plasma and synovial fluid-derived extracellular vesicles using an experimental model of equine osteoarthritis
JR Anderson, E Johnson, R Jenkins… - International journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) contribute to osteoarthritis pathogenesis through their release
into joint tissues and synovial fluid. Synovial fluid-derived EVs have the potential to be direct …
into joint tissues and synovial fluid. Synovial fluid-derived EVs have the potential to be direct …
Allogenic platelet-rich plasma and platelet-rich plasma extracellular vesicles alter the proteome of tenocytes in an in vitro equine model of tendon inflammation: A pilot …
E Clarke, A Jensen, A Gillen, D Bardell, M Senior… - bioRxiv, 2024 - biorxiv.org
Background: Tendon injuries are common in horses, often resulting in a high risk of reinjury.
Hemoderivative therapeutics including platelet-rich plasma (PRP) show promise but …
Hemoderivative therapeutics including platelet-rich plasma (PRP) show promise but …
Extracellular vesicles in osteoarthritis: from biomarkers to therapeutic potential
EJ Clarke, MJ Peffers - UK-Vet Equine, 2023 - magonlinelibrary.com
Equine osteoarthritis is a leading welfare concern. Currently, it can only be diagnosed in its
late stages–radiographically and upon clinical examination. There are no curative …
late stages–radiographically and upon clinical examination. There are no curative …
Exploring the Role of Extracellular Vesicles in Equine Musculoskeletal Pathologies and Associated Regenerative Therapies
EJ Clarke - 2023 - search.proquest.com
Horses are used in a variety of disciplines, including dressage, show jumping, eventing and
racing. Thus, the equine athlete is predisposed to the development of musculoskeletal …
racing. Thus, the equine athlete is predisposed to the development of musculoskeletal …
[HTML][HTML] Plasma and synovial fluid extracellular vesicles display altered microRNA profiles in horses with naturally occurring post-traumatic osteoarthritis: an …
SS Connard, AM Gaesser, EJ Clarke… - Journal of the …, 2024 - Am Vet Med Assoc
Representative images from radiocarpal, middle carpal, and metacarpophalangeal joints
classified as advanced post-traumatic osteoarthritis (PTOA) based on the modified …
classified as advanced post-traumatic osteoarthritis (PTOA) based on the modified …