The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …

The principles of mRNA decoding are conserved among all extant life forms. We present an
integrative view of all the interaction networks between mRNA, tRNA and rRNA: the intrinsic …

Nucleic acid modifications in DNA and RNA ubiquitously exist among all the three kingdoms
of life. This trait significantly broadens the genome diversity and works as an important …

RNAs are central to all gene expression through the control of protein synthesis. Four major
nucleosides, adenosine, guanosine, cytidine and uridine, compose RNAs and provide …

Transfer RNA (tRNA) molecules are sumptuously decorated with evolutionary conserved
post-transcriptional nucleoside modifications that are essential for structural stability and …

Abstract Iron–sulfur (Fe–S) clusters are prosthetic groups ensuring electron transfer
reactions, activating substrates for catalytic reactions, providing sulfur atoms for the …

Nucleic acids undergo naturally occurring chemical modifications. Over 100 different
modifications have been described and every position in the purine and pyrimidine bases …

In the past few years, thorough investigation of chemical modifications operated in the cells
on ribonucleic acid (RNA) molecules is gaining momentum. This new field of research has …

Highlights•Protozoan parasites encode a diverse and dynamic 'epitranscriptome'.•mRNA
modifications mediate unique mechanisms across a parasite's life cycle.•RNA modifications …

Retrograde transport of tRNAs from the cytoplasm to the nucleus was first described in
Saccharomyces cerevisiae and most recently in mammalian systems. Although the function …