Abstract Outer Membrane Vesicles (OMV) have received increased attention in recent years
as a vaccine platform against bacterial pathogens. OMV from Neisseria meningitidis …

The bacterium Neisseria gonorrhoeae causes the sexually transmitted infection (STI)
gonorrhoea, which has an estimated global annual incidence of 86.9 million adults …

Neisseria gonorrhoeae infection is an important public health issue, with an annual global
incidence of 87 million. N. gonorrhoeae infection causes significant morbidity and can have …

Abstract Background Neisseria gonorrhoeae and Neisseria meningitidis are closely-related
bacteria that cause a significant global burden of disease. Control of gonorrhoea is …

There are still great challenges for the effective treatment of infectious diseases, although
considerable achievement has been made by using antiviral and antimicrobial agents …

There is a pressing need for a gonorrhea vaccine due to the high disease burden
associated with gonococcal infections globally and the rapid evolution of antibiotic …

The concept of immunizing against gonorrhea has received renewed interest because of the
recent emergence of strains of Neisseria gonorrhoeae that are resistant to most currently …

Renewed interest in developing vaccines against Neisseria gonorrhoeae has been sparked
by the increasing threat of gonococcal antimicrobial resistance (AMR) and growing optimism …

The blood–brain barrier (BBB) is the protective sheath around the brain that protects the
sensitive microenvironments of the brain. However, certain pathogens, viruses, and bacteria …

Gonorrhea is a global health concern. Its etiological agent, Neisseria gonorrhoeae, rapidly
acquires antimicrobial resistance and does not confer protective immunity as a …