Human prostate cancer risk factors

DG Bostwick, HB Burke, D Djakiew… - … Journal of the …, 2004 - Wiley Online Library
Prostate cancer has the highest prevalence of any nonskin cancer in the human body, with
similar likelihood of neoplastic foci found within the prostates of men around the world …

Epigenetic modifications in prostate cancer

M Sugiura, H Sato, M Kanesaka… - … Journal of Urology, 2021 - Wiley Online Library
Prostate cancer is a major cause of cancer‐related deaths among men worldwide. In
addition to genomic alterations, epigenetic alterations accumulated in prostate cancer have …

Loss of let-7 up-regulates EZH2 in prostate cancer consistent with the acquisition of cancer stem cell signatures that are attenuated by BR-DIM

D Kong, E Heath, W Chen, ML Cher, I Powell… - PloS one, 2012 - journals.plos.org
The emergence of castrate-resistant prostate cancer (CRPC) contributes to the high mortality
of patients diagnosed with prostate cancer (PCa), which in part could be attributed to the …

Epigenetics in prostate cancer: biologic and clinical relevance

C Jerónimo, PJ Bastian, A Bjartell, GM Carbone… - European urology, 2011 - Elsevier
CONTEXT: Prostate cancer (PCa) is one of the most common human malignancies and
arises through genetic and epigenetic alterations. Epigenetic modifications include DNA …

The Epstein–Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA …

CN Tsai, CL Tsai, KP Tse… - Proceedings of the …, 2002 - National Acad Sciences
The latent membrane protein (LMP1) of Epstein–Barr virus (EBV) is expressed in EBV-
associated nasopharyngeal carcinoma, which is notoriously metastatic. Although it is …

Epigenetic changes in prostate cancer: implication for diagnosis and treatment

LC Li, PR Carroll, R Dahiya - Journal of the National Cancer …, 2005 - academic.oup.com
Prostate cancer is the most common noncutaneous malignancy and the second leading
cause of cancer death among men in the United States. DNA methylation and histone …

Epithelial-to-mesenchymal transition in prostate cancer: paradigm or puzzle?

JT Nauseef, MD Henry - Nature reviews Urology, 2011 - nature.com
The lethal consequences of prostate cancer are related to its metastasis to other organ sites.
Epithelial-to-mesenchymal transition (EMT) has received considerable attention as a …

Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects

MO Hoque, O Topaloglu, S Begum… - Journal of Clinical …, 2005 - ascopubs.org
Purpose Aberrant promoter hypermethylation of several known or putative tumor suppressor
genes occurs frequently during the pathogenesis of prostate cancers and is a promising …

Small RNA and transcriptional upregulation

V Portnoy, V Huang, RF Place… - Wiley Interdisciplinary …, 2011 - Wiley Online Library
Small RNA molecules, such as microRNA and small interfering RNA, have emerged as
master regulators of gene expression through their ability to suppress target genes in a …

USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy

YC Wang, YS Wu, CY Hung, SA Wang… - Nature …, 2018 - nature.com
We have previously demonstrated that USP24 is involved in cancer progression. Here, we
found that USP24 expression is upregulated in M2 macrophages and lung cancer cells …