Modulation of immune responses by particle size and shape

MV Baranov, M Kumar, S Sacanna… - Frontiers in …, 2021 - frontiersin.org
The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …

Biomaterials Facilitating Dendritic Cell‐Mediated Cancer Immunotherapy

H Dong, Q Li, Y Zhang, M Ding, Z Teng… - Advanced …, 2023 - Wiley Online Library
Dendritic cell (DC)‐based cancer immunotherapy has exhibited remarkable clinical
prospects because DCs play a central role in initiating and regulating adaptive immune …

Interactions between nanoparticles and dendritic cells: from the perspective of cancer immunotherapy

J Jia, Y Zhang, Y Xin, C Jiang, B Yan, S Zhai - Frontiers in oncology, 2018 - frontiersin.org
Dendritic cells (DCs) are the primary antigen-presenting cells and play key roles in the
orchestration of the innate and adaptive immune system. Targeting DCs by nanotechnology …

Elastic Nanovaccine Enhances Dendritic Cell‐Mediated Tumor Immunotherapy

Q Li, Z Teng, J Tao, W Shi, G Yang, Y Zhang, X Su… - Small, 2022 - Wiley Online Library
Nanovaccine‐based immunotherapy (NBI) has the ability to initiate dendritic cell (DC)‐
mediated tumor‐specific immune responses and maintain long‐term antitumor immune …

Physical and chemical profiles of nanoparticles for lymphatic targeting

X Ke, GP Howard, H Tang, B Cheng, MT Saung… - Advanced drug delivery …, 2019 - Elsevier
Nanoparticles (NPs) have been gaining prominence as delivery vehicles for modulating
immune responses to improve treatments against cancer and autoimmune diseases …

Poly-L-lactic acid fillers improved dermal collagen synthesis by modulating M2 macrophage polarization in aged animal skin

S Oh, JH Lee, HM Kim, S Batsukh, MJ Sung, TH Lim… - Cells, 2023 - mdpi.com
Poly-L-lactic acid (PLLA) fillers correct cutaneous volume loss by stimulating fibroblasts to
synthesize collagen and by augmenting the volume. PLLA triggers the macrophage-induced …

Peptide hydrogels and nanostructures controlling biological machinery

J Mitrovic, G Richey, S Kim, MO Guler - Langmuir, 2023 - ACS Publications
Peptides are versatile building blocks for the fabrication of various nanostructures that result
in the formation of hydrogels and nanoparticles. Precise chemical functionalization promotes …

Exploiting autophagy-regulative nanomaterials for activation of dendritic cells enables reinforced cancer immunotherapy

YH Guan, N Wang, ZW Deng, XG Chen, Y Liu - Biomaterials, 2022 - Elsevier
Dendritic cells (DCs), as the most powerful antigen presenting cells, play a critical role in
regulating immune response and anti-tumor process. However, the immunosuppressive …

Self-assembled peptide nanostructures for functional materials

MS Ekiz, G Cinar, MA Khalily, MO Guler - Nanotechnology, 2016 - iopscience.iop.org
Nature is an important inspirational source for scientists, and presents complex and elegant
examples of adaptive and intelligent systems created by self-assembly. Significant effort has …

A microparticle platform for STING-targeted immunotherapy enhances natural killer cell-and CD8+ T cell-mediated anti-tumor immunity

R Watkins-Schulz, P Tiet, MD Gallovic, RD Junkins… - Biomaterials, 2019 - Elsevier
Immunotherapies have significantly improved cancer patient survival, but response rates are
still limited. Thus, novel formulations are needed to expand the breadth of immunotherapies …