Modulation of immune infiltration of ovarian cancer tumor microenvironment by specific subpopulations of fibroblasts

J Wang, FHC Cheng, J Tedrow, W Chang, C Zhang… - Cancers, 2020 - mdpi.com
Simple Summary The ovarian cancer tumor microenvironment is made up of ovarian cancer
cells along with a milieu of proteins and normal cells, including fibroblasts, immune cells …

DAISM-DNNXMBD: Highly accurate cell type proportion estimation with in silico data augmentation and deep neural networks

Y Lin, H Li, X Xiao, L Zhang, K Wang, J Zhao, M Wang… - Patterns, 2022 - cell.com
Understanding the immune cell abundance of cancer and other disease-related tissues has
an important role in guiding disease treatments. Computational cell type proportion …

Effects of molecular Iodine/Chemotherapy in the immune component of breast cancer tumoral microenvironment

O Cuenca-Micó, E Delgado-González, B Anguiano… - Biomolecules, 2021 - mdpi.com
Molecular iodine (I2) induces apoptotic, antiangiogenic, and antiproliferative effects in breast
cancer cells. Little is known about its effects on the tumor immune microenvironment. We …

Acid–Base Homeostasis and Implications to the Phenotypic Behaviors of Cancer

Y Zhou, W Chang, X Lu, J Wang… - Genomics, Proteomics …, 2023 - academic.oup.com
Acid–base homeostasis is a fundamental property of living cells, and its persistent disruption
in human cells can lead to a wide range of diseases. In this study, we conducted a …

SSMD: a semi-supervised approach for a robust cell type identification and deconvolution of mouse transcriptomics data

X Lu, SW Tu, W Chang, C Wan, J Wang… - Briefings in …, 2021 - academic.oup.com
Deconvolution of mouse transcriptomic data is challenged by the fact that mouse models
carry various genetic and physiological perturbations, making it questionable to assume …