Glutamate receptor antagonists as fast-acting therapeutic alternatives for the treatment of depression: ketamine and other compounds

MJ Niciu, ID Henter, DA Luckenbaugh… - Annual review of …, 2014 - annualreviews.org
The N-methyl-d-aspartate (NMDA) receptor antagonist ketamine has rapid and potent
antidepressant effects in treatment-resistant major depressive disorder and bipolar …

To use or not to use: an update on licit and illicit ketamine use

JH Li, B Vicknasingam, Y Cheung, W Zhou… - Substance abuse and …, 2011 - Taylor & Francis
Ketamine, a derivative of phencyclidine that was developed in the 1960s, is an anesthetic
and analgesic with hallucinogenic effects. In this paper, the pharmacological and …

Application of a sewage-based approach to assess the use of ten illicit drugs in four Chinese megacities

U Khan, ALN van Nuijs, J Li, W Maho, P Du, K Li… - Science of the Total …, 2014 - Elsevier
Sewage-based epidemiology was applied for the first time to a number of mainland Chinese
megacities. The application monitored influents to 9 sewage treatment plants (STPs) to …

Impact of wastewaters and hospital effluents on the occurrence of controlled substances in surface waters

AYC Lin, XH Wang, CF Lin - Chemosphere, 2010 - Elsevier
We have investigated the occurrence of controlled drugs in two rivers, two wastewater
treatment plants (WWTPs) and five hospital effluents in Taipei, Taiwan, and report here the …

[HTML][HTML] Gender differences in subjective discontinuation symptoms associated with ketamine use

WY Chen, MC Huang, SK Lin - Substance Abuse Treatment, Prevention …, 2014 - Springer
Background Recent substance abuse research indicates gender differences in the
substance-related epidemiology, biological responses, progression to dependence, medical …

[HTML][HTML] Adolescent substance use behavior and suicidal behavior for boys and girls: a cross-sectional study by latent analysis approach

PW Wang, CF Yen - BMC psychiatry, 2017 - Springer
Background Adolescent suicidal behavior may consist of different symptoms, including
suicidal ideation, suicidal planning and suicidal attempts. Adolescent substance use …

Differences in prevalence, socio-behavioral correlates, and psychosocial distress between club drug and hard drug use in Taiwan: Results from the 2014 National …

WJ Chen, SC Wu, WI Tsay, YT Chen, PC Hsiao… - International Journal of …, 2017 - Elsevier
Background This study examined variation between users of 'club'and 'hard'drugs in Taiwan
in terms of prevalence of use and demographics and psychosocial characteristics. Methods …

Cognitive profile of ketamine-dependent patients compared with methamphetamine-dependent patients and healthy controls

LJ Wang, CK Chen, SK Lin, YC Chen, K Xu… - …, 2018 - Springer
Background Ketamine has emerged as a major substance of abuse worldwide and has
been listed with methamphetamine (METH) as two of the most widely available illicit …

[HTML][HTML] Effects of early ketamine exposure on cerebral gray matter volume and functional connectivity

CC Hung, YH Liu, CC Huang, CY Chou, CM Chen… - Scientific reports, 2020 - nature.com
Ketamine has been used for medical purposes, most typically as an anesthetic, and recent
studies support its use in the treatment of depression. However, ketamine tends to be …

Ketamine use disorder: preclinical, clinical, and neuroimaging evidence to support proposed mechanisms of actions

L Vines, D Sotelo, A Johnson, E Dennis… - Intelligent …, 2022 - mednexus.org
Ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, has been
exclusively used as an anesthetic in medicine and has led to new insights into the …