Pregnancy-specific glycoproteins: complex gene families regulating maternal-fetal interactions.

T Moore, GS Dveksler - International Journal of …, 2014 - search.ebscohost.com
The pregnancy-specific glycoproteins (PSGs) are the most abundant trophoblastic proteins
in maternal blood during human pregnancy and they appear to be exclusive to species with …

Pregnancy-specific glycoproteins: evolution, expression, functions and disease associations

T Moore, JM Williams, MA Becerra-Rodriguez… - …, 2022 - rep.bioscientifica.com
Pregnancy-specific glycoproteins (PSGs) are members of the immunoglobulin superfamily
and are closely related to the predominantly membrane-bound CEACAM proteins. PSGs are …

The evolution and population diversity of human-specific segmental duplications

MY Dennis, L Harshman, BJ Nelson, O Penn… - Nature ecology & …, 2017 - nature.com
Segmental duplications contribute to human evolution, adaptation and genomic instability
but are often poorly characterized. We investigate the evolution, genetic variation and …

The Molecular Evolution of Cytochrome P450 Genes within and between Drosophila Species

RT Good, L Gramzow, P Battlay, T Sztal… - Genome biology and …, 2014 - academic.oup.com
We map 114 gene gains and 74 gene losses in the P450 gene family across the phylogeny
of 12 Drosophila species by examining the congruence of gene trees and species trees …

Frequent nonallelic gene conversion on the human lineage and its effect on the divergence of gene duplicates

A Harpak, X Lan, Z Gao… - Proceedings of the …, 2017 - National Acad Sciences
Gene conversion is the copying of a genetic sequence from a “donor” region to an
“acceptor.” In nonallelic gene conversion (NAGC), the donor and the acceptor are at distinct …

PSG9 Stimulates Increase in FoxP3+ Regulatory T-Cells through the TGF-β1 Pathway

K Jones, A Ballesteros, M Mentink-Kane, J Warren… - PLoS …, 2016 - journals.plos.org
The pregnancy-specific glycoproteins (PSGs) are a family of proteins secreted by the
syncytiotrophoblast of the placenta and are the most abundant trophoblastic proteins in …

De novo intrachromosomal gene conversion from OPN1MW to OPN1LW in the male germline results in Blue Cone Monochromacy

E Buena-Atienza, K Rüther, B Baumann, R Bergholz… - Scientific reports, 2016 - nature.com
X-linked cone dysfunction disorders such as Blue Cone Monochromacy and X-linked Cone
Dystrophy are characterized by complete loss (of) or reduced L-and M-cone function due to …

Increased mutation rate and interlocus gene conversion within human segmental duplications

MR Vollger, WS DeWitt, PC Dishuck, WT Harvey… - bioRxiv, 2022 - biorxiv.org
Single-nucleotide variants (SNVs) within segmental duplications (SDs) have not been
systematically assessed because of the difficulty in mapping short-read sequence data to …

Duplication history and molecular evolution of the rbcS multigene family in angiosperms

K Yamada, II Davydov, G Besnard… - Journal of Experimental …, 2019 - academic.oup.com
Abstract Ribulose-1, 5-bisphosphate carboxylase/oxygenase (RuBisCO) is considered to be
the main enzyme determining the rate of photosynthesis. The small subunit of the protein …

Interlocus gene conversion explains at least 2.7% of single nucleotide variants in human segmental duplications

BL Dumont - BMC genomics, 2015 - Springer
Background Interlocus gene conversion (IGC) is a recombination-based mechanism that
results in the unidirectional transfer of short stretches of sequence between paralogous loci …