Cell lines are in vitro model systems that are widely used in different fields of medical
research, especially basic cancer research and drug discovery. Their usefulness is primarily …

Background The aim of the present review is to discuss how the promising field of
biobanking can support health care research strategies. As the concept has evolved over …

This paper develops the conceptual framework of" sex contextualism" for the study of sex-
related variables in biomedical research. Sex contextualism offers an alternative to binary …

OBJECTIVES: Cell lines derived from human ovarian and endometrial cancers, and their
immortalized non-malignant counterparts, are critical tools to investigate and characterize …

Lung cancer cell lines have made a substantial contribution to lung cancer translational
research and biomedical discovery. A systematic approach to initiating and characterizing …

Athymic nude mice, a murine strain bearing spontaneous deletion in the Foxn1 gene that
causes deteriorated or absent thymus (which results in inhibited immune system with …

Cell lines are used extensively in research and drug development as models of normal and
cancer tissues. However, a substantial proportion of cell lines is mislabelled or replaced by …

The commercial production of monoclonal antibodies (mAbs) has revolutionized the
treatment of many diseases, including cancer, multiple sclerosis, and rheumatoid arthritis …

Recently, increasing numbers of cell culture experiments with 3D spheroids presented better
correlating results in vivo than traditional 2D cell culture systems. 3D spheroids could offer a …

Simple Summary Although rare, uveal melanoma (UM) is the most common cancer that
develops inside adult eyes. The prognosis is poor, since 50% of patients will develop lethal …