T-type, low-voltage activated, calcium channels, now designated Cav3 channels, are
involved in a wide variety of physiological functions, especially in nervous systems. Their …

T-type channels are low-voltage-activated calcium channels that contribute to a variety of
cellular and physiological functions, including neuronal excitability, hormone and …

Dysfunction in sodium channels and their ankyrin scaffolding partners have both been
implicated in neurodevelopmental disorders, including autism spectrum disorder (ASD). In …

T-type calcium channels perform crucial physiological roles across a wide spectrum of
tissues, spanning both neuronal and non-neuronal system. For instance, they serve as …

Kcc2 plays a critical role in determining the efficacy of synaptic inhibition, however, the
cellular mechanisms neurons use to regulate its membrane trafficking, stability and activity …

ABSTRACT T-type Ca2+ channels and TRPA1 expressed in sensory neurons are involved
in pain. We previously demonstrated a functional interaction of these channels under …

Rare genetic variants in ANK2, which encodes ankyrin-B, are associated with
neurodevelopmental disorders (NDDs); however, their pathogenesis is poorly understood …

The ANK2 gene encodes for ankyrin-B (ANKB), one of 3 members of the ankyrin family of
proteins, whose name is derived from the Greek word for anchor. ANKB was originally …

Aldosterone is a steroid hormone produced in the zona glomerulosa (ZG) of the adrenal
cortex. The most prominent function of aldosterone is the control of electrolyte homeostasis …

Ankyrin B (AnkB) is an adaptor and scaffold for motor proteins and various ion channels that
is ubiquitously expressed, including in the brain. AnkB has been associated with …