Targeting serine-glycine-one-carbon metabolism as a vulnerability in cancers
W Sun, R Liu, X Gao, Z Lin, H Tang, H Cui, E Zhao - Biomarker Research, 2023 - Springer
The serine-glycine-one-carbon (SGOC) metabolic pathway is critical for DNA methylation,
histone methylation, and redox homeostasis, in addition to protein, lipid, and nucleotide …
histone methylation, and redox homeostasis, in addition to protein, lipid, and nucleotide …
Multi-omics reveals that green pea (Pisum sativum L.) hull supplementation ameliorates non-alcoholic fatty liver disease via the SHMT2/glycine/mTOR/PPAR-γ …
F Guo, H Xiong, R Tsao, X Wen, J Liu, D Chen… - Food & Function, 2023 - pubs.rsc.org
Diets rich in various active ingredients may be an effective intervention strategy for non-
alcoholic fatty liver disease (NAFLD). The green pea hull (GPH) is a processing by-product …
alcoholic fatty liver disease (NAFLD). The green pea hull (GPH) is a processing by-product …
Disturbed intracellular folate homeostasis impairs autophagic flux and increases hepatocytic lipid accumulation
WY Chi, GH Lee, MJ Tang, BH Chen, WL Lin, TF Fu - BMC biology, 2024 - Springer
Background Metabolic associated fatty liver disease (MAFLD), a prevalent liver disorder
affecting one-third of the global population, encompasses a spectrum ranging from fatty liver …
affecting one-third of the global population, encompasses a spectrum ranging from fatty liver …
[HTML][HTML] Effects of dietary soybean lecithin on growth performances, body composition, serum biochemical parameters, digestive and metabolic abilities in largemouth …
W Yang, J Wu, R Song, Z Li, X Jia, P Qian, H Zhang… - Aquaculture …, 2023 - Elsevier
We conducted an 8-week feeding trial to explore the effects of dietary soybean lecithin (SBL)
on growth performance and metabolic abilities in juvenile largemouth bass Micropterus …
on growth performance and metabolic abilities in juvenile largemouth bass Micropterus …
[HTML][HTML] Estrogen alleviates liver fibrosis and restores metabolic homeostasis in ovariectomy-induced liver injury and carbon tetrachloride (CCl4) exposure
ZY Chen, MJ Panga, X Zhang, S Qiao, S Chen… - European Journal of …, 2024 - Elsevier
Aim Given estrogen's recognized regulatory influence on diverse metabolic and immune
functions, this study sought to explore its potential impact on fibrosis and elucidate the …
functions, this study sought to explore its potential impact on fibrosis and elucidate the …
Investigating the Impact of Pineapple–Whey Protein Fermentation Products on Cefixime-Induced Intestinal Flora Dysbiosis in Mice Using 16S Sequencing and …
J Luo, S Xiao, D Ma, J Xiang, B Wang, Y Cai, J Wang - Foods, 2024 - mdpi.com
In our previous study, a new fermented food (PWF) created by utilizing pineapple by-
products and whey proteins as a matrix via co-fermentation with lactic acid bacteria and …
products and whey proteins as a matrix via co-fermentation with lactic acid bacteria and …
Metabolic disturbance and transcriptomic changes induced by methyl triclosan in human hepatocyte L02 cells
J An, Y Yi, J Jiang, W Yao, G Ren… - Toxicology Research, 2023 - academic.oup.com
Purpose: Methyl triclosan (MTCS) is one of the biomethylated by-products of triclosan (TCS).
With the increasing use of TCS, the adverse effects of MTCS have attracted extensive …
With the increasing use of TCS, the adverse effects of MTCS have attracted extensive …
LINC00885 promotes development of lung adenocarcinoma through AKT/mTOR/P70 signaling LINC00885 may regulate migration, proliferation, and invasion of lung …
Z Liang, W Wan, W Su, B Dai, KX Wang, G Lin, B Deng… - 2024 - researchsquare.com
Purpose Previous studies have demonstrated the role of long non-coding RNAs (lncRNAs)
in lung adenocarcinoma (LUAD). Methods Results RNA sequencing analysis identified high …
in lung adenocarcinoma (LUAD). Methods Results RNA sequencing analysis identified high …
[引用][C] Targeting SHMT2 to up-regulate the expression of ESR1 enhances the anti-breast cancer effect of tamoxifen
L WANG, X BI, H KONG, F MO, Y WANG, J HU, Y QIN