Chronic graft-versus-host disease (cGvHD) remains a prominent barrier to allogeneic
hematopoietic stem cell transplantion as the leading cause of nonrelapse mortality and …

Chronic Graft-versus-Host Disease is a life-threatening inflammatory condition that affects
many patients after allogeneic hematopoietic stem cell transplantation. Although we have …

Understanding the factors which shape T-lymphocyte immunity is critical for the
development and application of future immunotherapeutic strategies in treating …

As the primary site of T-cell development, the thymus dictates immune competency of the
host. The rates of thymus function are not constant, and thymus regeneration is essential to …

The thymus has the ability to regenerate from acute injury caused by radiation, infection, and
stressors. In addition to thymocytes, thymic epithelial cells in the medulla (mTECs), which …

The thymus is a unique primary lymphoid organ that supports the production of self‐tolerant
T‐cells essential for adaptive immunity. Intrathymic microenvironments are …

Improving regeneration of damaged thymus is important for reconstituting T-cell immunity.
Interleukin-22 (IL-22) was proved to improve thymus regeneration through recovering thymic …

Disorders of immune dysregulation following heart transplantation in children have been
reported; however, the management of such disorders remains uncertain and challenging …

Allogeneic hematopoietic stem cell transplantation (HSCT) is the treatment of preference for
numerous malignant and non-malignant hemopathies. The outcome of this approach is …

The thymus has the ability to regenerate from acute injury caused by radiation, infection, and
stressors. In addition to thymocytes, thymic epithelial cells in the medulla (mTECs), which …