Epigenetic remodeling is a molecular hallmark of gliomas, and it has been identified as a
key mediator of glioma progression. Epigenetic dysregulation contributes to gliomagenesis …

Increasing evidence suggests that besides mutational and molecular alterations, the
immune component of the tumor microenvironment also substantially impacts tumor …

Gliomas are the most prevalent and aggressive brain tumors, exhibiting high proliferation,
abnormal glycolysis, and poor prognosis. LncRNAs act as regulatory molecules and play …

With the success of immunotherapy in cancer, understanding the tumor immune
microenvironment (TIME) has become increasingly important; however in pediatric brain …

Recent studies demonstrated that pyroptosis plays a crucial role in shaping the tumor-
immune microenvironment. However, the influence of pyroptosis on lower-grade glioma …

Isocitrate dehydrogenase (IDH) is a key enzyme in normal metabolism and homeostasis.
However, mutant forms of IDH are also defining features of a subset of diffuse gliomas. In …

Tumor-associated macrophages (TAMs) residing in the tumor microenvironment (TME) are
characterized by their pivotal roles in tumor progression, antitumor immunity, and TME …

The parasellar region is the anatomical area around the sella turcica that represents a
crucial crossroad for important adjacent structures. Several distinct tumors can primarily …

Simple Summary Gliomas are the most common primary brain tumors. These cancers are
universally fatal with limited treatment options. Glioma cells co-opt non-cancerous cells …

Oxidative stress refers to the process of reactive oxide species (ROS) increase in human
body due to various factors, which leads to oxidative damage in human tissues. Current …