Neurotoxins: free radical mechanisms and melatonin protection

RJ Reiter, LC Manchester… - Current …, 2010 - ingentaconnect.com
Toxins that pass through the blood-brain barrier put neurons and glia in peril. The damage
inflicted is usually a consequence of the ability of these toxic agents to induce free radical …

A critical review of polychlorinated biphenyls metabolism, metabolites, and their correlation with oxidative stress

J Liu, Y Tan, E Song, Y Song - Chemical Research in Toxicology, 2020 - ACS Publications
Polychlorinated biphenyls (PCBs) are notorious persistent organic pollutants that were
banned in the last century. However, PCBs still remain ubiquitous in the ecosystem due to …

Melatonin and metabolic regulation: a review

M Navarro-Alarcón, FJ Ruiz-Ojeda… - Food & function, 2014 - pubs.rsc.org
Human life expectancy has increased over the past 50 years due to scientific and medical
advances and higher food availability. However, overweight and obesity affect more than …

Alzheimer's disease and related neurodegenerative disorders: implication and counteracting of melatonin

M Pohanka - Journal of Applied Biomedicine, 2011 - Elsevier
Age related neurodegenerative disorders are becoming a serious public health problem.
Alzheimer's disease (AD) is a progressive disease pathologically recognizable by …

Thyroxine restores hippocampal neurogenesis and synaptogenesis in a male rat model of carbimazole-induced hypothyroidism: a histological study

EA Farag, SA Filobbos, NM Afifi, ST Mahmoud… - Beni-Suef University …, 2023 - Springer
Background Adult-onset hypothyroidism has a deleterious effect on hippocampal cognitive
and memory functions. This study was performed to evaluate the possible therapeutic effect …

Effect of quercetin on haematobiochemical and histological changes in the liver of polychlorined biphenyls‐induced adult male Wistar rats

K Selvakumar, S Bavithra, S Suganya… - Journal of …, 2013 - Wiley Online Library
Polychlorinated biphenyls exposure damages the rat liver cells. Hematological parameters
such as hemoglobin, packed cell volume, red‐blood cells, white‐blood cells, neutrophils …

Neuro-amelioration of cinnamaldehyde in aluminum-induced Alzheimer's disease rat model

HN Mustafa - Journal of histotechnology, 2020 - Taylor & Francis
Aluminum (Al) is a neurotoxic substance which has played an important role in the etiology,
pathogenesis, and development of amyloid-β (Aβ) plaques. This study was carried out to …

L-Theanine alleviates the neuropathological changes induced by PCB (Aroclor 1254) via inhibiting upregulation of inflammatory cytokines and oxidative stress in rat …

T Sumathi, D Asha, G Nagarajan, A Sreenivas… - Environmental …, 2016 - Elsevier
The present study is aimed at evaluating the protective role of l-theanine on aroclor 1254-
induced oxidative stress in rat brain. Intraperitoneal administration of Aroclor 1254 (2 mg/kg …

Protective role of quercetin on PCBs-induced oxidative stress and apoptosis in hippocampus of adult rats

K Selvakumar, S Bavithra, M Suganthi… - Neurochemical …, 2012 - Springer
Polychlorinated biphenyls (PCBs) exposure produces neurodegeneration and induces
oxidative stress. Neuroprotective role of quercetin, on PCBs induced apoptosis in …

The glutathione system and its regulation by neurohormone melatonin in the central nervous system

JH Limon-Pacheco… - Central Nervous System …, 2010 - ingentaconnect.com
The glutathione system includes reduced (GSH) and oxidized (GSSG) forms of glutathione;
the enzymes required for its synthesis and recycling, such as gamma-glutamate cysteine …