ATP-dependent chromatin remodeling: genetics, genomics and mechanisms

DC Hargreaves, GR Crabtree - Cell research, 2011 - nature.com
Macromolecular assemblies that regulate chromatin structure using the energy of ATP
hydrolysis have critical roles in development, cancer, and stem cell biology. The ATPases of …

Chromatin remodelling during development

L Ho, GR Crabtree - Nature, 2010 - nature.com
New methods for the genome-wide analysis of chromatin are providing insight into its roles
in development and their underlying mechanisms. Current studies indicate that chromatin is …

MicroRNA-mediated conversion of human fibroblasts to neurons

AS Yoo, AX Sun, L Li, A Shcheglovitov, T Portmann… - Nature, 2011 - nature.com
Neurogenic transcription factors and evolutionarily conserved signalling pathways have
been found to be instrumental in the formation of neurons,. However, the instructive role of …

[图书][B] Developmental neuropsychology: A clinical approach

V Anderson, E Northam, J Wrennall - 2018 - taylorfrancis.com
This fully updated edition of Developmental Neuropsychology: A Clinical Approach
addresses key issues in child neuropsychology with a unique emphasis on evidence …

From neural development to cognition: unexpected roles for chromatin

JL Ronan, W Wu, GR Crabtree - Nature Reviews Genetics, 2013 - nature.com
Recent genome-sequencing studies in human neurodevelopmental and psychiatric
disorders have uncovered mutations in many chromatin regulators. These human genetic …

Chromatin remodeling BAF (SWI/SNF) complexes in neural development and disorders

G Sokpor, Y Xie, J Rosenbusch, T Tuoc - Frontiers in molecular …, 2017 - frontiersin.org
The ATP-dependent BRG1/BRM associated factor (BAF) chromatin remodeling complexes
are crucial in regulating gene expression by controlling chromatin dynamics. Over the last …

Branching out: mechanisms of dendritic arborization

YN Jan, LY Jan - Nature Reviews Neuroscience, 2010 - nature.com
Type-specific dendrite morphology is a hallmark of the neuron and has important functional
implications in determining what signals a neuron receives and how these signals are …

MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

AS Yoo, BT Staahl, L Chen, GR Crabtree - Nature, 2009 - nature.com
One of the most distinctive steps in the development of the vertebrate nervous system occurs
at mitotic exit when cells lose multipotency and begin to develop stable connections that will …

The BAF complex in development and disease

A Alfert, N Moreno, K Kerl - Epigenetics & chromatin, 2019 - Springer
The ATP-dependent chromatin remodelling complex BAF (= mammalian SWI/SNF complex)
is crucial for the regulation of gene expression and differentiation. In the course of evolution …

A cis-regulatory map of the Drosophila genome

N Nègre, CD Brown, L Ma, CA Bristow, SW Miller… - Nature, 2011 - nature.com
Systematic annotation of gene regulatory elements is a major challenge in genome science.
Direct mapping of chromatin modification marks and transcriptional factor binding sites …