Targeted liposomal drug delivery: a nanoscience and biophysical perspective

Y Liu, KMC Bravo, J Liu - Nanoscale horizons, 2021 - pubs.rsc.org
Liposomes are a unique platform for drug delivery, and a number of liposomal formulations
have already been commercialized. Doxil is a representative example, which uses …

[HTML][HTML] Temperature-sensitive polymers to promote heat-triggered drug release from liposomes: Towards bypassing EPR

M Amin, T Lammers, TLM Ten Hagen - Advanced Drug Delivery Reviews, 2022 - Elsevier
Heat-triggered drug release from temperature-sensitive nanocarriers upon the application of
mild hyperthermia is a promising approach to achieve site-specific delivery of drugs. The …

Nanomaterials meet zebrafish: Toxicity evaluation and drug delivery applications

HR Jia, YX Zhu, QY Duan, Z Chen, FG Wu - Journal of Controlled Release, 2019 - Elsevier
With the rapid development of engineered nanomaterials for various applications, in vivo
toxicological studies for evaluating the potential hazardous effects of nanomaterials on …

Fusogenic coiled-coil peptides enhance lipid nanoparticle-mediated mRNA delivery upon intramyocardial administration

Y Zeng, M Estapé Senti, MCI Labonia… - ACS …, 2023 - ACS Publications
Heart failure is a serious condition that results from the extensive loss of specialized cardiac
muscle cells called cardiomyocytes (CMs), typically caused by myocardial infarction (MI) …

Zebrafish as a preclinical in vivo screening model for nanomedicines

S Sieber, P Grossen, J Bussmann, F Campbell… - Advanced drug delivery …, 2019 - Elsevier
The interactions of nanomedicines with biological environments is heavily influenced by
their physicochemical properties. Formulation design and optimization are therefore key …

Cholesterol-assisted bacterial cell surface engineering for photodynamic inactivation of gram-positive and gram-negative bacteria

HR Jia, YX Zhu, Z Chen, FG Wu - ACS Applied Materials & …, 2017 - ACS Publications
Antibacterial photodynamic therapy (PDT), which enables effective killing of regular and
multidrug-resistant (MDR) bacteria, is a promising treatment modality for bacterial infection …

Nanocarriers for biomedicine: From lipid formulations to inorganic and hybrid nanoparticles

R Kashapov, A Ibragimova, R Pavlov… - International Journal of …, 2021 - mdpi.com
Encapsulation of cargoes in nanocontainers is widely used in different fields to solve the
problems of their solubility, homogeneity, stability, protection from unwanted chemical and …

[HTML][HTML] Novel fusion peptides deliver exosomes to modify injectable thermo-sensitive hydrogels for bone regeneration

S Ma, J Wu, H Hu, Y Mu, L Zhang, Y Zhao, X Bian… - Materials Today Bio, 2022 - Elsevier
Injectable thermo-sensitive hydrogels composed of small intestinal submucosa (SIS) with
exosomes derived from bone marrow mesenchymal stem cells (BMSCs) are desired for …

Antibody variable region engineering for improving cancer immunotherapy

H Lou, X Cao - Cancer Communications, 2022 - Wiley Online Library
The efficacy and specificity of conventional monoclonal antibody (mAb) drugs in the clinic
require further improvement. Currently, the development and application of novel antibody …

[HTML][HTML] Coiled coil-based therapeutics and drug delivery systems

J Utterström, S Naeimipour, R Selegård… - Advanced Drug Delivery …, 2021 - Elsevier
Coiled coils are characterized by an arrangement of two or more α-helices into a superhelix
and one of few protein motifs where the sequence-to-structure relationships to a large extent …