The epithelial–mesenchymal transition (EMT) is one of the processes by which epithelial
cells transdifferentiate into mesenchymal cells in the developmental stage, known as …

Staging lymph nodes (LN) is crucial in diagnosing and treating cancer metastasis.
Biotechnologies for the specific localization of metastatic lymph nodes (MLNs) have …

Triple-negative breast cancer (TNBC) is a subtype of breast cancer with poor outcome and
lacks of approved targeted therapy. Overexpression of epidermal growth factor receptor …

Overcoming distant metastasis stands as a paramount challenge in enhancing the outcomes
of breast cancer treatments. Thus, delving deeper into comprehending the intricate …

Cancer is a challenging to treat disease with a high mortality rate worldwide, nevertheless
advances in science has led to a decrease in the number of death cases caused by cancer …

Background Epithelial-to-mesenchymal transition (EMT) and cancer stem-like cells (CSLCs)
play crucial role in tumor metastasis and drug-resistance. Disheveled3 (DVL3) is involved in …

The process of neutrophil extracellular traps (NETs) formation, called NETosis, is a peculiar
death modality of neutrophils, which was first observed as an immune response against …

Gastric cancer remains one of the most common deadly diseases and lacks effective
targeted therapies. In the present study, we confirmed that the signal transducer and …

Chemotherapy, the most widely accepted treatment for malignant tumors, is dependent on
cell death induced by various drugs including antimetabolites, alkylating agents, mitotic …

Tumor metastasis is a major cause of cancer mortality. However, little is known regarding the
regulation of abnormal cholesterol metabolism in hepatocellular carcinoma (HCC) …